Morphological Tumor Markers: General Aspects and Diagnostic Relevance

ISBN-13: 9783642713583 / Angielski / Miękka / 2011 / 398 str.

Gerhard Seifert

Opis

New methods in immunocytochemistry and hybridization techniques enable the pathologist active in diagnosis to clarify more effectively problems in the classification and prognosis of tumors. By adopting these methods into his diagnostic repertoire it will be possible to create a closer, more productive connection between morphological diagnosis and clinical work. This volume gives the reader an up-to-date general survey from international experts of the method, technique and practical application of these new procedures.

Spis treści

Monoclonal Antibodies to Human Tumor Antigens.- Biochemical Markers for Human Cancer.- Immunohistochemical Methods for the Demonstration of Tumor Markers.- Epithelial Tumor Markers: Cytokeratins and Tissue Polypeptide Antigen (TPA).- Epithelial Tumor Markers: Oncofetal Antigens (Carcinoembryonic Antigen, Alpha Fetoprotein) and Epithelial Membrane Antigen.- Epithelial Tumor Markers: Special Markers of Glandular Differentiation.- Mesenchymal Tumor Markers: Intermediate Filaments.- Mesenchymal Tumor Markers: Special Proteins and Enzymes.- Proteoglycans and the Intercellular Tumor Matrix.- Basal Membrane Antigens as Tumor Markers.- Lectins and Blood Group Substances as “Tumor Markers”.- Neuroendocrine Tumor Markers.- Morphological Markers in Neuro-Oncology.- Viral Tumor Markers.- Cell, Tissue and Organ Specific Tumor Markers: An Overview.- Indexed in ISR.