Molecular Sensors and Nanodevices: Principles, Designs and Applications in Biomedical Engineering

ISBN-13: 9781455776313 / Angielski / Twarda / 2013 / 491 str.

John Zhang

Opis

With applications ranging from medical diagnostics to environmental monitoring, molecular sensors (also known as biosensors, chemical sensors, or chemosensors), along with emerging nanotechnologies offer not only valuable tools but also unlimited possibilities for engineers and scientists to explore the world. New generation of functional microsystems can be designed to provide a variety of small scale sensing, imaging and manipulation techniques to the fundamental building blocks of materials. This book provides comprehensive coverage of the current and emerging technologies of molecular sensing, explaining the principles of molecular sensor design and assessing the sensor types currently available. Having explained the basic sensor structures and sensing principles, the authors proceed to explain the role of nano/micro fabrication techniques in molecular sensors, including MEMS, BioMEMS, MicroTAS among others. The miniaturization of versatile molecular sensors opens up a new design paradigm and a range of novel biotechnologies, which is illustrated through case studies of groundbreaking applications in the life sciences and elsewhere. As well as the techniques and devices themselves, the authors also cover the critical issues of implantability, biocompatibility and the regulatory framework.
The book is aimed at a broad audience of engineering professionals, life scientists and students working in the multidisciplinary area of biomedical engineering. It explains essential principles of electrical, chemical, optical and mechanical engineering as well as biomedical science, intended for readers with a variety of scientific backgrounds. In addition, it will be valuable for medical professionals and researchers. An online tutorial developed by the authors provides learning reinforcement for students and professionals alike.

• Reviews of state-of-the-art molecular sensors and nanotechnologies
• Explains principles of sensors and fundamental theories with homework problems at the end of each chapter to facilitate learning
• Demystifies the vertical integration from nanomaterials to devices design
• Covers practical applications the recent progress in state-of-the-art sensor technologies
• Includes case studies of important commercial products
• Covers the critical issues of implantability, biocompatibility and the regulatory framework

Spis treści

1. Introduction to Molecular Sensors Introduction2. Fundamentals of Nano/Microfabrication and Scale Effect 3. Microfluidics basics and total analytical systems4. Electrical transducers: electrochemical sensors and FET-based molecular sensors5. Optical transducers: optical molecular sensors and optical spectroscopy6. Mechanical transducers: cantilevers, acoustic wave sensors and thermal sensors 7. Implantable sensors