Molecular Physiology of Growth

ISBN-13: 9780521471107 / Angielski / Twarda / 1997 / 184 str.

London) P. T. Loughna (Royal Veterinary College;J. M. Pell

Opis

In this diverse synthesis of recent research, the regulation of growth in response to environmental and genetic stimuli is discussed in reference to tissues and cells, as well as the whole animal. Many issues are addressed in detail, including how hormones and growth factors regulate animal growth in the developing embryo and what processes at the molecular level determine the growth patterns of different tissues. The text draws contrasts between regulation in fetal and adult tissues, and among different tissues such as the CNS, bone and muscle. Functional chapters focus on the molecular links between mechanical tension and muscle growth, for example, while other chapters review the roles of specific molecules such as growth hormone.

Recenzje

"This book is a great resource for beginners as well as those who already use this technique, because each chapter contains its own methods section." James Konopka, The Quarterly Review of Biology

Spis treści

1. Role of growth hormone in growth regulation D. J. Flint, K. Akinsaya, P. J. Crilly, P. Johnston and D. Wynick; 2. Insulin-like growth factor-1 and its binding proteins: role in postnatal growth J. M. Pell and J. Glassford; 3. Growth factor interactions in epiphyseal chondrogenesis D. J. Hill; 4. Developmental changes in the CNS response to injury: growth factor and matrix interactions A. Logan; 5. The role of transforming factor ß during cardiovascular development M. C. Dickson, J. S. Martin and R. J. Ackhurst; 6. Tenascin: an extracellular matrix protein associated with bone growth E. J. Mackie and S. Ramsey; 7. Compartmentation of protein synthesis, mRNA targeting and c-myc expression during mucle hypertrophy and growth J. Hesketh; 8. The role of mechanical tension in regulating muscle growth and phenotype P. T. Loughna and C. Brownson; 9. The prenatal influence on postnatal muscle growth N. C. Stickland and C. M. Dwyer; 10. Genomic imprinting and intrauterine growth retardation G. E. Moore, P. R. Bennett, Z. Ali, R. U. Khan and J. I. Vaughan.