Molecular Pathogenesis of Virus Infections

ISBN-13: 9780521832489 / Angielski / Twarda / 2005 / 358 str.

Society for General Microbiology; P. Digard; A. A. Nash

Opis

This symposium book covers the central factors that influence the pathogenicity of virus and prion infections. Virus and prion diseases remain a major public health threat, in both developed and developing countries. The worldwide HIV pandemic is one example of a newly emerged virus disease, and older human viruses such as influenza, papilloma, and the hepatitis viruses still cause major health problems. Some viruses may also establish persistent infections which can lead to the development of chronic diseases, including cancer.

Spis treści

Preface; 1. Adaptive immune responses J. L. Whitton; 2. T-cell responses and dengue haemorrhagic fever G. Screaton and J. Mongkolsapaya; 3. The immune response to human immunodeficiency virus type 1 (HIV-1) E. Turnbull and P. Borrow; 4. Persistent RNA virus infections C. M. Dixon, L. Breakwell, G. Barry and J. K. Fazakerley; 5. Exotic virus pathogenesis S. Nichol; 6. Molecular approaches to the pathogenesis of feline coronaviruses C. Dye and S. Siddell; 7. The transmissible spongiform encephalopathies J. C. Manson and R. M. Barron; 8. Influenza virus pathogenicity R. G. Webster, A. S. Lipatov and E. Hoffmann; 9. RNAi as an antiviral mechanism and therapeutic approach R. P. van Rij and R. Andino; 10. Neurons and host immunity conspire to maintain herpes simplex virus in a latent state M. L. Freeman, V. Decman and R. L. Hendricks; 11. Hepatitis C virus disruption of interferon signalling pathways and evasion of innate intracellular antiviral defences S. M. Lemon and K. Li; 12. Human papillomaviruses and their effects on cell cycle control and apoptosis L. Gray, C. Jolly and C. S. Herrington; 13. Intracellular antiviral defence mechanisms: the power of interferon-regulated restriction factors O. Haller, F. Weber and G. Kochs; 14. Poxvirus immune evasion A. Alcami; 15. Evasion of host defence systems by African swine fever virus L. K. Dixon; 16. Murid herpesvirus 4 as a model for gammaherpesvirus pathogenesis J. P. Stewart, D. Hughes, L. Roaden and B. Ebrahimi; Index.