Molecular Mechanisms of Aging

ISBN-13: 9783540527329 / Angielski / Miękka / 1990 / 206 str.

Konrad Beyreuther; Gotthard Schettler

Opis

A high-level text on the molecular and genetic aspects of human ageing with reference to cognitive functions and age-related diseases."

Spis treści

Cognitive Functions and Aging.- The Brain Disease of Aging - Epidemiology and Risk Factors of Senile Dementia (Alzheimer').- Cognition Related Functional, Praxis and Feeding Changes in CNS Aging and Alzheimer's Disease and their Developmental Analogies.- Genetics and Biology of Aging.- Genetical Aspects of Aging.- Aging and DNA Repair.- Gene Expression.- Transcription Factor Regulation in Brain: Focus on Activity and NMDA Dependent Regulation.- New Methods for Detecting DNA Sequence Variation in Relation to Aging.- Regulation of the Amyloid Gene of Alzheimer's Disease.- Membranes and Aging.- The Molecular Biology of Down Syndrome.- Aging of Cell Membrane Molecules: Band 3 and Senescent Cell Antigen in Neural Tissue.- Essential Macromolecular Structures for the Function of the Myelin Membrane of Central Nervous System.- Models.- Transgenic Mouse Model of Autosomal Dominant Disease: Familial Amyloidotic Polyneuropathy.- Somatostatin and Brain Aging.- Molecular Approaches to Age-Related Diseases.- Amyloidosis.- Amyloid ßA4 Protein Deposition in Alzheimer's Disease and Down's Syndrome.- Alzheimer's Disease and Animal Models.- Acknowledgements.- List of Participants.