Molecular Hydrogen in Health and Disease

ISBN-13: 9783031473746 / Angielski

Jan Slezak; Branislav Kura

Spis treści

1. Hydrogen: From Stars to Fuel to Medicine..............................................................

LeBaron, Sharpe, Pyatakovich, Artamonov

2. An exploration of the direct biological targets of molecular hydrogen.................

Hancock, May, LeBaron, Punampalam, Russell

3. Prospects of hydrogen medicine based on its protective effects on mitochondrial function.......................................................................................................................

Hirano, Ichikawa, Sato, Takefuji, Li, Satoh

4. Molecular hydrogen: A new treatment strategy of mitochondrial disorders.......

Gvozdjakova, Kucharska, Sumbalova, Rausova, Kura, Bartolcicova, Slezak

5. Autonomic cardiac regulation in response to exercise and molecular hydrogen administration in well-trained athletes....................................................................

Botek, Krejci, Sladeckova, McKune

6. The Clinical Use of Hydrogen as a Medical Treatment..........................................

Xie, Song

7. Homeostatic and endocrine response underlying protective effects by molecular hydrogen...................................................................................................

Noda, Nazarov

8. Radiation-induced heart disease: potential role for molecular hydrogen.............

Kura, Pavelkova, Kalocayova, Slezak

9. Short-lasting supplementation with molecular hydrogen and vitamin E upregulates myocardial connexin-43 in irradiated and non-irradiated rat heart............................................................................................................................

Szeiffova Bacova, Andelova, Sykora, Kura, Kalocayova, Slezak, Tribulova

10. Molecular hydrogen: a new protective tool against radiation-induced toxicity

Vlkovicova, Kura, Pavelkova, Kalocayova

11. Role of Matrix Metalloproteinases in Effects of Molecular Hydrogen.................

Botanska, Pecnikova, Kura, Slezak, Barancik

12. Perioperative mitigation of oxidative stress with molecular  hydrogen during simulated heart transplantation in pigs...................................................................

Kura, Szeiffova Bacova, Barancik, Sykora, Okruhlicova, Tribulova, Bolli, Kalocayova, LeBaron, Andelova, Slezak

13. Application of Hydrogen in Hemodialysis: A brief review with emphasis on the quantification of dissolved H2...................................................................................

Mouzakis, Khadka, da Silva, Mottaghy

14. Hydrogen as a potential therapeutic approach in the treatment of cancer: from bench to bedside.........................................................................................................

Rouzbehani, Mahmoudvand, Goudarzi, Fakouri, Farokhi, Sokhangouy, Ghorbani, Avan, Nazari, Khazaei

15. The Role of the Smallest Molecule  Hydrogen Overcoming Ageing-Related Disease........................................................................................................................

Wenjing, Rahman, Chaodeng, Vongdouangchanh, Kim, Lee

16. Dihydrogen and Hepatic Function: Systematic Review and Meta-Analysis........

Todorovic, Ostojic

17. Hydrogen-rich water using as a modulator of gut microbiota and managing the inflammatory bowel diseases....................................................................................

Yaghoubi, Soleimanpour, Khazaei

18. Effects of Molecular Hydrogen in the  Pathophysiology and Management of Metabolic and Non-communicable Diseases............................................................

Singh, Tarnava, Fedacko, Fatima, Rupee, Sumbalova

19. Consumption of Hydrogen-Treated Foods Provides Nutritional and Health Benefits.......................................................................................................................

Alwazeer

20. Differential effects of carbohydrates on the generation of hydrogen and methane in low- and high-methane-producing rats................................................

Medvedev, Ivanova, Belousova, Toshchakov, Krylova, Shirokov, Obolenskaya, Kuropatkina, Bondarenko, Gartseev

21. Natural Biomolecules, Plant Extracts and Molecular Hydrogen – New Antioxidant Alternatives in the Management of Male Infertility..........................

Tvrda, Duracka, Ivanisova

22. Comparison of free-radical scavenging activity of various sources of molecular hydrogen.....................................................................................................................

Valachova, Kura, Slezak, Mach, Soltes

23. Development of a preclinical tool for measuring percutaneous transfer of dihydrogen, with a view to optimizing medical devices adapted to focal therapies in dermatology .........................................................................................

Salomez-Ihl, Tanguy, Boucher, Pascal Mousselard, Bedouch, Stephanou, Alcaraz, Cinquin

24. Intraosseous Administration of Molecular Hydrogen: A Novel Technique – From Molecular Effects To Tissue Regeneration....................................................

Artamonov, LeBaron, Sokov, Kornilova, Pyatakovich, Minenko

25. Perspective of nanomaterials and nanomedicine procedures in molecular hydrogen therapy.......................................................................................................

Luby

26. The emergence, development, and future mission of hydrogen medicine and biology........................................................................................................................

Ohta

Blurb

Molecular hydrogen (H2) has emerged as a promising therapeutic and preventive medical gas. Hydrogen gas has garnered significant attention in recent years due to its remarkable antioxidant and anti-inflammatory properties. H2 exhibits exceptional pharmacokinetics, swiftly traversing cellular biomembranes to access subcellular organelles indirectly regulating hormones and cytokines through various signal transduction pathways. H2 has the potential to address a wide range of issues, including clinical medical treatment in the areas of healthcare: myocardial ischemia, heart failure, cardiac arrest, metabolic syndrome, advanced-stage cancer, inflammatory diseases, Alzheimer's dementia, aging-related disorders, sports activities, and even beauty, agriculture, etc.

Selected world-known authors in the field provide readers with a comprehensive overview of molecular hydrogen's remarkable effects and its physical, chemical, and therapeutic properties and potential in biomedical applications. This contributed volume fills the current gap in information and is intended for everyone who wants to be better informed about the wide possibilities of using molecular hydrogen. However, it is mainly intended for use by medical students, physiologists, pharmacologists, physicians, and other healthcare personnel who can use molecular hydrogen to improve the health of everyone who needs it.