Molecular Genetics of Colorectal Neoplasia: A Primer for the Clinician

ISBN-13: 9781402076114 / Angielski / Twarda / 2003 / 174 str.

James M. Church; Graham Casey

Opis

Molecular Genetics of Colorectal Neoplasia A Primer for the Clinician provides the latest information on the genetics of colorectal cancer within a context of basic genetics, describing the subject in understandable language and making it clinically relevant. In this way, clinicians can become familiar with genetic terms and techniques related to colorectal neoplasia, providing a background upon which to build an appreciation of future advances and an ability to include them in the practicalities of patient care. This edition is intended for the healthcare provider or industry concerned with colorectal neoplasia: including general and colorectal surgeons, pathologists, oncologists, gastroenterologists, internal medicine and family practice physicians, nurses, geneticists, counsellors, registry co-ordinators, epidemiologists, and statisticians.

Spis treści

1. An Introduction to Genetics.- 2. Changes in Gene Function.- 3. Molecular Genetics Methods Simplified.- 4. Genes and Cell Homeostasis.- 5. Pathology of Colorectal Neoplasia.- 6. Molecular Genetics of Colorectal Neoplasia.- 7. Family History: The Key That Unlocks the Door to Familial Colorectal Cancer.- 8. Patients and Their Families With a Family History of Colorectal Cancer.- 9. Inherited Syndromes: Familial Adenomatous Polyposis, Hereditary Non Polyposis Colorectal Cancer, and the Hamartomatous Polyposes.- 10. A Registry For Inherited Colorectal Cancer.- 11. Practical Applications of the Molecular Genetics of Colorectal Cancer.