Molecular Genetics and Personalized Medicine

ISBN-13: 9781627039239 / Angielski / Miękka / 2014 / 246 str.

D. Hunter Best; Jeffrey J. Swensen

Opis

Genetic testing has become commonplace, and clinicians are frequently able to use knowledge of an individual's specific genetic differences to guide their course of action. Molecular Genetics and Personalized Medicine highlights developments that have been made in the field of molecular genetics and how they have been applied clinically. It will serve as a useful reference for physicians hoping to better understand the role of molecular medicine in clinical practice. In addition, it should also prove to be an invaluable resource for the basic scientist that wants to better understand how advances in the laboratory are being moved from the bench to the bedside. All chapters are written by experts in their fields and include the most up to date medical information. The authors simplify complex genetic concepts and focus on practical patient related issues. The book will be of great value to pathologists, hematologists/oncologists, clinical geneticists, high-risk obstetricians, general practitioners, and physicians in all other medical specialties who utilize genetic testing to direct therapy.

Recenzje

From the reviews:

"With its diagrams and images, this is a useful reference for those who want to better understand molecular genetic testing and its role in personalized medicine. ... this book is intended for a broad medical audience including pathologists, hematologists/oncologists, general practitioners, clinical geneticists, and anyone else involved in the use of genetic testing to direct patient therapy. ... This book would be a worthy addition to the library of anyone who ... desires to learn more about the role of molecular genetics in personalized medicine." (Jamie Boone, Doody's Review Service, June, 2012)

Spis treści

01. Molecular Genetic Testing in the Genomic Era
Charles Sailey and Ferrin Wheeler

02. Array Comparative Genomic Hybridization in Cytogenetics and Molecular Genetics
S. Hussain Askree and Madhuri Hegde

03. Pharmacogenomics: Tailoring Treatment Based on Genotype
Alan H.B. Wu

04. Somatic Alterations and Targeted Therapy
Allison M. Cushman-Vokoun

05. Genome Wide Association Studies in Disease Risk Calculation: The Role of Bioinformatics in Patient Care
Todd L. Edwards, Digna R. Velez Edwards, Marylyn D. Ritchie

06. Presymptomatic Genetic Testing: Shifting the Emphasis from Reaction to Prevention
Irene H. Hung, John C. Carey

07. Prenatal Testing: Screening, Diagnosis and Preimplantation Genetic Diagnosis
Eugene Pergament

08. Newborn Screening  for Metabolic Disorders
Marzia Pasquali and Nicola Longo

09. The Role of Genetic Counseling in Everyday Medical Practice
Kimberly J. Hart, Erin E. Baldwin, and D. Hunter Best

10. Direct-to-Consumer Genetic Testing
Caroline F. Wright and Daniel G. MacArthur

O autorze

D. Hunter Best 
University of Utah School of Medicine, Salt Lake City, UT, USA

Jeffrey J. Swensen
University of Utah School of Medicine, Salt Lake City, UT, USA