Molecular Dynamics - Practical Application : - Mechanism underlying the resistance to prion diseases in rabbits : a technology review from MIT and in 7 languages

ISBN-13: 9783846548431 / Angielski / Miękka / 2011 / 168 str.

Jiapu Zhang

Opis

In chemistry, physics, biophysics, biochemistry, biomedicine, bioinformatics, applied mathematics and theoretical physics, Molecular dynamics (MD) simulating physical movements of atoms and molecules is widely applied. Amber and Gromacs etc are very popular and practical MD packages. This book applies these packages to biomolecules and materials. It provides comprehensive MD materials and methods to put MD into actions. This book clearly has a value to MD simulation staff (in research or teaching) in the fields of chemistry, physics, biophysics, biochemistry, biomedicine, bioinformatics, applied mathematics and theoretical physics. This book fully illuminates MD application to prion proteins from many points of view. The author was awarded numerous world-wide impacts and fame for the successful MD application. Prion diseases can be caused by the body s own proteins not requiring either DNA, RNA, or both; they are "structural conformational" diseases so very proper to be studied by MD technologies. Rabbits, dogs and horses are reported to be immune to prion diseases. The author using MD technologies preliminarily revealed some surprising secrets from rabbits against prion diseases

O autorze

Dr. Jiapu Zhang finished his BSc, MSc, MSc, PhD degrees in 1993, 1996, 2000 and 2004 respectively. During 1996-1998, he lectured in Shandong University,China. He did his 1st Postdoc at CSIRO. Since 2005, he has worked in CSIRO, Ballarat and Melbourne Universities. In 2011, MIT's report on his prion results has awarded him world-wide impacts & fame.