Molecular Detection of Human Papilloma Virus in Oral Carcinoma : Sequence-based genotyping, Salivary microRNA deregulation in oral carcinoma

ISBN-13: 9783659846328 / Angielski / Miękka / 2016 / 156 str.

Maysaa Kadhim Al-Malkey; Ahmed A.H. Abbas; Nahi Y. Yaseen

Opis

The role of human papilloma virus (HPV) as a potential etiological factor in oral carcinoma (OC) has been debated for the last three decades. The pathogenesis of HPV in cervical cancer is well established and the International Agency for Research on Cancer has accepted the role of HPV in several head and neck cancers. However, evidence for a definitive link between HPV and OC remains controversial. Sequence based genotyping (SBG) offers users several advantages including a generic sample preparation method, a uniform bioinformatics workflow strategy to achieve genotyping goals tailored to individual species regardless of the availability of a reference sequence, the most distinguishing feature is the ability to genotype any population structure regardless whether parental data is included, and the ability to co-dominantly score single nucleotide polymorphism (SNP) markers segregating in populations.

O autorze

Dr. Maysaa Kadhim Al-Malkey, PhD in Medical Microbiology studied at College of Medicine,Al-Nahrain University. Lecturer/Researcher at Tropical-Biological Research Unit, College of Science, University of Baghdad. She is interested in cancer causing viruses and salivary microRNA gene expression as a new diagnostic tool for carcinomas