Modern Pharmaceutics

ISBN-13: 9781841847733 / Angielski / Twarda / 2010 / 656 str.

Opis

With over 100 illustrations, Volume 1 addresses the core disciplines of pharmaceutics (absorption, PK, excipients, tablet dosage forms, and packaging), and explores the challenges and paradigms of pharmaceutics.Key topics in Volume 1 include:principles of drug absorption, chemical kinetics, and drug stabilitypharmacokineticsthe effect of route of administration and distribution on drug actionin vivo imaging of dose forms: gamma scintigraphy, PET imaging NMR, MRI, etc. powder technologyexcipient design and characterizationpreformulationoptimization techniques in pharmaceutical formulation and processingdisperse and surfactant systemsthe solid state, tablet dosage forms, coating processes, and hard and soft shell capsulesparenteral products

Spis treści

Volume 1:1. Pharmaceutics: New Challenges, New ParadigmsAlexander T. Florence and Juergen Siepmann2. Principles of Drug AbsorptionMichael Mayersohn3. PharmacokineticsDavid W. A. Bourne4. Factors Influencing Oral Drug Absorption and Drug AvailabilityJuergen Siepmann, Florence Siepmann, and Alexander T. Florence5. Effect of Route of Administration and Distribution on Drug ActionMaureen D. Donovan6. In Vivo Imaging of Dosage FormsZheng-Rong Lu7. Chemical Kinetics and Drug StabilityDavid Attwood and Rolland I. Poust8. The Solid StateAlastair J. Florence9. Excipient Design and CharacterizationGraham Buckton10. PreformulationGavin W. Halbert11. Disperse SystemsWandee Rungseevijitprapa, Florence Siepmann, Juergen Siepmann, and Ornlaksana Paeratakul12. SurfactantsDavid Attwood13. Tablet Dosage FormsMurat Turkoglu and Adel Sakr14. Hard- and Soft-Shell CapsulesLarry L. Augsburger15. Parenteral ProductsJames C. Boylan and Steven L. NailIndex