Mild Hypertension: Current Controversies and New Approaches

ISBN-13: 9783798506473 / Angielski / Miękka / 1984 / 172 str.

K. Hayduk

Opis

There is clear evidence that in severe hypertension lowering blood pressure, by drug therapy decreases the incidence of major cardiovascular events.

Spis treści

Introduction: Some neurological aspects of blood pressure control.- Central and peripheral control of blood pressure.- Central nervous system control of blood pressure.- Discussion.- Blood pressure control and the peripheral sympathetic nervous system.- Discussion.- Baroreflex function and centrally acting antihypertensive drugs.- Discussion.- Haemodynamic effects of antihypertensive agents in man.- Discussion.- Vascular autonomy and its relation to the action of antihypertensive drugs.- Discussion.- General discussion.- Therapeutic consequences.- Therapeutic decisions in mild hypertension: an introductory overview.- When to treat? Recent trials in mild hypertension. Epidemiological data and conclusions.- Discussion.- Current assessment of the stepped-care treatment of mild hypertension: diuretics, beta-blockers, vasodilators versus Clonidine.- Discussion.- Use of centrally-acting agonists in the treatment of mild hypertension in the elderly patient.- Discussion.- Sympathetic nervous system activity in the obese hypertensive patient: potential role for central alpha-adrenoreceptor agonists.- Discussion.- Clonidine for treating patients with mild hypertension and angina pectoris.- New pharmacological approaches in the treatment of mild hypertension. The potential role of converting enzyme inhibitors and calcium blocking agents.- Discussion.- General discussion.- Advances in treatment.- Rate-controlled drug delivery and the reduction of risk.- Clonidine rate — controlled system: technology and kinetics.- Discussion.- Absorption of clonidine from a transdermal therapeutic system when applied to different body sites.- Discussion.- Clinical experience with clonidine TTS.- Discussion.- Clinical effectiveness of the transdermal route of antihypertensive treatment.- Discussion.- Roundtable discussion on the use of transdermal medication: clinical characteristics and skin reactions.- Panel discussion: the role of clonidine in the treatment of mild hypertension.- Concluding remarks.- Participants.