Microsatellite Instability and Progression of Cancer : Microsatellite Instability is raised in Gallbladder Cancer

ISBN-13: 9783659234866 / Angielski / Miękka / 2012 / 152 str.

Rachana Singh; Hari Shankar Shukla; Haushla Prasad Pandey

Opis

Microsatellite are the section of DNA in which a short sequence of nucleotide is repeated multiple time. This form of genetic destablization is associated with defective DNA mismatch repair functions. This works examine MSI in cancer Gallbladder, Breast and Oral cavity. The finding are significant in Gallbladder cancer, which is a leathal cancer. This indicates greater genetic instability in Gallbladder cancer.

O autorze

Rachana Singh, Ph.D. Research in Microsatellite Instability and Progression in Cancer. Research Fellow in the Department of Biochemistry, Banaras Hindu University, Varanasi, India.