Microrna in Human Malignancies

ISBN-13: 9780128222874 / Angielski / Miękka / 2022

Massimo Negrini; George A. Calin; Carlo Croce

Spis treści

SECTION 1: miRNAs involvement in basic mechanisms of cancer development 1. Overview on miRNA classification, biogenesis, and functions 2. microRNA in cancer: overview 3. miR-15/16 in human malignancies 4. microRNAs and TP53 regulation 5. microRNAs involvement in Invasion and metastasis 6. microRNAs and metabolism 7. microRNAs in inflammation processes

SECTION 2: miRNAs methodologies 8. Wet-lab methods for miRNA analysis 9. Bioinformatics utilities, web resources and integrative strategies for the analysis of miRNA regulatory networks 10. Computational Resources for Analysis of miRNA Targetome 11. miRNA bioinformatics and pathway analysis

SECTION 3: miRNAs involvement in therapeutics / theranostics 12. Opportunities of miRNAs in cancer therapeutics

SECTION 4: miRNAs involvement in human cancer: pathophysiology and translational opportunities 13. Pathophysiology roles and translational opportunities of miRNAs in acute leukemias 14. Pathophysiology roles and translational opportunities of miRNAs in CLL 15. Pathophysiology roles and translational opportunities of miRNAs in Lymphoma 16. Pathophysiology roles and translational opportunities of miRNAs in Breast cancer 17. Pathophysiology roles and translational opportunities of miRNAs in colorectal cancer 18. Pathophysiology roles and translational opportunities of miRNAs in Lung cancer 19. Pathophysiology roles and translational opportunities of miRNAs in Mesothelioma 20. Pathophysiology roles and translational opportunities of miRNAs in Renal cancer 21. Pathophysiology roles and translational opportunities of miRNAs in Pancreatic cancer 22. Pathophysiology roles and translational opportunities of miRNAs in Prostate cancer 23. Pathophysiology roles and translational opportunities of miRNAs in Hepatocarcinoma 24. Pathophysiology roles and translational opportunities of miRNAs in Ovarian cancer 25. Pathophysiology roles and translational opportunities of miRNAs in Bladder cancer 26. Pathophysiology roles and translational opportunities of miRNAs in Cutaneous Melanoma 27. Pathophysiology roles and translational opportunities of miRNAs in Brain tumors 28. Pathophysiology roles and translational opportunities of miRNAs in Sarcomas