Microbiome in Neurological Disease

ISBN-13: 9780323991766 / Angielski / Twarda / 2022 / 308 str.

Tim Sampson

Spis treści

Preface: Unraveling the complex contributions of the microbiome to neurological diseases
Timothy Sampson
1. Intersections of the microbiome and early neurodevelopment
Helen Vuong
2. Microbiome influences on neuro-immune interactions
Malu G. Tansey and Brittney Otero
3. The genomes of Parkinson's disease
Haydeh Payami
4. Experimental contributions of the microbiome to Parkinson's disease
Ali Keshavarzian, Christopher Goetz, Deborah Ann Hall, Richard A. Manfready, Robin Voigt and Christopher Forsyth
5. The foundations of microbiome contributions to Alzheimer's disease
Sam Sisodia and Hemraj Dodiya
6. Immunologic pathways by which the gut microbiota influences Alzheimer's disease
Laurie Cox and Carolin Wasen
7. Role of the gut microbiome in Huntington's Disease
Anthony Hannan
8. The microbiome in multiple sclerosis, from etiology to therapeutics
Ashutosh K. Mangalam
9. The microbiome and epilepsy
Elaine Hsiao
10. Influence of the microbiome in recovery of traumatic nervous system injury
Timothy Sampson and Adam Hamilton
11. Role of the microbiome in chronic and visceral pain
Michael Burton

O autorze

Dr. Sampson's primary research interests lie in understanding how the complex interactions between indigenous microbes and the host can shape neurological responses, during neurodegenerative disease and neurological injury. His academic career to date has uniquely positioned him with training across broad topics: microbiology, immunology, genetics, molecular biology, and biochemistry. Following postdoctoral studies at Caltech, with Dr. Sarkis Mazmanian, he utilized his background in bacterial genetics and host-pathogen interactions to explore how indigenous microbes influence Parkinson's disease (PD). These activities have laid the foundation for his independent career exploring host-microbe interactions at the interface of PD, Alzheimer's disease (AD) and other neurological illnesses--diseases historically studied within the context of the central nervous system.