Microbial Endocrinology: Interkingdom Signaling in Infectious Disease and Health

ISBN-13: 9781489984197 / Angielski / Miękka / 2014 / 316 str.

Mark Lyte; Primrose P. E. Freestone

Opis

Microbial endocrinology represents a newly emerging interdisciplinary field that is formed by the intersection of the fields of neurobiology and microbiology. This book will introduce a new perspective to the current understanding not only of the factors that mediate the ability of microbes to cause disease, but also to the mechanisms that maintain normal homeostasis. The discovery that microbes can directly respond to neuroendocrine hormones, as evidenced by increased growth and production of virulence-associated factors, provides for a new framework with which to investigate how microorganisms interface not only with vertebrates, but also with invertebrates and even plants. The reader will learn that the neuroendocrine hormones that one most commonly associates with mammals are actually found throughout the plant, insect and microbial communities to an extent that will undoubtedly surprise many, and most importantly, how interactions between microbes and neuroendocrine hormones can influence the pathophysiology of infectious disease. The book is intended for anyone who is interested in the interaction of microbes with both the animal and plant kingdoms. This book is an interdisciplinary effort that will cover the presence of neuroendocrine hormones in vertebrates, invertebrates, plants and microorganisms themselves and how the ability of bacteria to directly respond to these neuroendocrine hormones introduces completely new paradigms in understanding infectious disease pathogenesis.

Spis treści

1. Microbial endocrinology: A Personal Journey Mark Lyte Ph.D. – Texas Tech University Health Sciences Center, Lubbock, TX, US 2. Evolutionary considerations of neurotransmitters in microbial, plant and animal Cells Victoria V. Roshchina, Ph.D. – Russian Academy of Sciences, Pushchino, Moscow Region, USSR 3. Mechanisms by which catecholamine stress hormones induce growth in Gram-negative and Gram-positive bacteria Primrose P.E. Freestone, Ph.D. and Sara M. Sandrini, PhD – Leicester University, Leicester, UK 4. Dietary catechols and their relationship to microbial endocrinology Neil Shearer, PhD and Nicholas J. Walton, PhD. – Institute of Food Research, Norwich, UK 5. Interactions between bacteria and the gut mucosa: Do enteric neurotransmitters acting on the mucosal epithelium influence intestinal colonization or infection? David R. Brown, Ph.D. – University of Minnesota, Minnesota, US and Benedict T. Green, Ph.D. – USDA, Logan, UT, US 6. Modulation of the interaction of enteric bacteria with intestinal mucosa by stress-related catecholamines Mark P. Stevens, Ph.D. – Institute for Animal Health, Berkshire, UK 7. The role of microbial endocrinology in periodontal disease Anthony Roberts, Ph.D., BDS – School of Dentistry, University of Manchester, Manchester, UK 8. Staphylococci, catecholamine inotropes and hospital-acquired infections Primrose P.E. Freestone, Ph.D, Noura Al-Dayan, MSc. – Leicester University, Leicester, UK and Mark Lyte, Ph.D. – Texas Tech University Health Sciences Center, Lubbock, TX, US 9. The microbial endocrinology of Pseudomonas aeruginosa John C. Alverdy, M.D., FACS, Kathleen Romanowski M.D., Olga Zaborina Ph.D., Alex Zaborina Ph.D. – University of Chicago, Chicago, IL, US 10. Mechanisms of stress-related modulation of upper and lower respiratory tract infections. Cordula Stover, Ph.D., MD – Leicester University, Leicester, UK 11. Psychological stress, immunity, and the effects on indigenousmicroflora Michael Bailey, Ph.D. – Ohio State University, Columbus, OH, US 12. The epinephrine/norepinephrine/autoinducer-3 inter-kingdom signaling system in Escherichia coli O157:H7 Cristiano Moreira and Vanessa Sperandio, Ph.D. – University of Texas Southwestern Medical Center, Dallas, TX, US 13. Molecular profiling: catecholamine modulation of gene expression in enteropathogenic bacteria Bradley Bearson, Ph.D. – USDA, Ames, IA and Scot Dowd, Ph.D. – USDA, Lubbock, TX, US 14. Microbial signaling compounds as endocrine effectors Aruna Jahoor, PhD, Simon Williams, PhD and Kendra Rumbaugh, Ph.D. – Texas Tech University Health Sciences Center, Lubbock, TX, US 15. Mycolic endocrinology Karl V. Clemons, Ph.D. – California Institute for Medical Research, San Jose, CA, US. Jata Shankar, Ph.D. – Santa Clara Valley Medical Center, San Jose, CA, US and David A. Stevens, Ph.D. – Stanford University, Stanford, CA, US 16. Experimental design considerations for in vitro microbial endocrinology investigations. Richard Haigh Ph.D. – University of Leicester, Leicester, UK

Blurb

About this book

Microbial endocrinology represents a newly emerging interdisciplinary field that is formed by the intersection of the fields of neurobiology and microbiology. It is the intent of this book to introduce a new perspective to the current understanding not only of the factors that mediate the ability of microbes to cause disease, but also to the mechanisms that maintain normal homeostasis. The discovery that microbes can both synthesize and directly respond to neuroendocrine hormones provides for a new framework with which to investigate how microorganisms interface not only with vertebrates, but also with invertebrates and even plants.

The reader will learn that neuroendocrine hormones, most commonly associated with mammals, are actually found throughout the plant, insect and microbial kingdoms to an extent that will undoubtedly surprise many, and most importantly, highlight how interactions between microbes and neuroendocrine hormones influence health and the pathophysiology of infectious disease. This book will lead its readers to the understanding that through eons of association with eukaryotic organisms, bacteria have evolved specific detection systems for neuroendocrine hormones, which they utilize not only to "sense" their environment, but also to co-op products of neurophysiological responses for their own survival.

 

About the Editors

Prof. Mark Lyte, Ph.D., M.S., MT(ASCP) is a Professor in the Department of Pharmacy Practice, and adjunct Professor in the Departments of Internal Medicine and Microbiology and Immunology, Texas Tech University Health Sciences Center. Prof. Lyte conducted experiments in 1991 that subsequently led him shortly thereafter to propose and found the field of microbial endocrinology. In addition to having served on scientific review panels for the National Institutes of Health and other worldwide agencies, Prof. Lyte has been awarded the Joseph Susman Memorial Award for Surgical Infectious Disease Research and was named a finalist for the NIH Director’s Pioneer Award.

Dr. Primrose Freestone, BSc(Hons), PhD, PGCE is a Lecturer in Clinical Microbiology, in the Department of Infection, Immunity and Inflammation, University of Leicester. Dr. Freestone was the first to identify tyrosine phosphorylation as a regulatory mechanism in bacteria, and to elucidate the mechanisms by which stress hormones induce bacterial growth. She is also an inventor in the fields of microbial diagnostics and dietary bioactives, and has been awarded Fellowships to develop entrepreneurial activities in life science biotechnology.