Microbe-Vector Interactions in Vector-Borne Diseases

ISBN-13: 9780521843126 / Angielski / Twarda / 2004 / 383 str.

Ed. Stephen H. Gillespie; Anne Osbourn; Geoffrey L. Smith

Opis

Several billion people are at daily risk of life-threatening vector-borne diseases such as malaria, trypanosomiasis and dengue. This volume describes the way in which the causal pathogens of such diseases interact with the vectors that transmit them, detailing the biological adaptations that enable pathogens to live with their vectors and, in some circumstances, to control them. This knowledge has led to novel preventative strategies in the form of antibiotics and new vaccines which are targeted not at the pathogen itself but at its specific vector.

Recenzje

'The authors describe the advantages of insects as vectors and their numerous barriers to infection, including physico-chemical barriers, the gut, haemolymph, and the salivary glands themselves.' ASM News

Spis treści

Preface; 1. Vector-borne diseases B. W. J. Mahy; 2. Evolution of tick-borne disease systems S. E. Randolph; 3. Insect transmission of viruses S. Blanc; 4. Interactive silencing of host gene expression S. W. Ding; 5. Reducing the prevalence of Borrelia in ticks A. G. Barbour; 6. Bunyavirus/mosquito interactions R. M. Elliott; 7. How do mosquito vectors live with their viruses? S. Higgs 8. Induction of vector competence S. Weaver; 9. Environmental influences on arbovirus infections and vectors P. S. Mellor; 10. Vector immunity N. A. Ratcliffe and M. M. A. Whitten; 11. Transmission of plant viruses by nematodes S. MacFarlane and D. J. Robinson; 12. Wolbachia host-symbiont interactions M. J. Taylor; 13. Pathogenic strategies of Anaplasma phagocytophilum, a unique bacterium that colonizes neutrophils J. A. Carlyon and E. Fikrig; 14. Interactions of Yersinia pestis with its flea vector that lead to the transmission of plague B. J. Hinnebusch; 15. Transgenic malaria P. W. Atkinson; 16. Vaccines targeting vectors G. A. T. Targett; Index.