Methods of Cancer Diagnosis, Therapy and Prognosis: Breast Carcinoma

ISBN-13: 9789048178582 / Angielski / Miękka / 2010 / 728 str.

M. A. Hayat

Opis

The enormity of the global healthcare costs vical. One-fifth of all cancers worldwide as a result of cancer infliction cannot be are caused by a chronic infection, for overemphasized. There are more than 100 example, human papilloma virus (HPV) types of cancers; any part of the body can causes cervical cancer and hepatitis B be affected. More than 11 million people virus (HBV) causes liver cancer. Tobacco are diagnosed with cancer every year, and use is the most common preventable cause it is estimated that there will be 16 mil- of cancer in the world. Approximately, lion new cases per year by the year 2020. 168,000 cancer deaths are expected to be In 2005, 7. 6 million people died of can- caused by tobacco use. Approximately, cer, that is, 13% of the 58 million deaths 40% of cancer could be prevented, mainly worldwide. It is estimated that 9 million by not using tobacco, having a healthy people will die from cancer worldwide in diet, being physically active, preventing 2015 and 11. 4 million will die in 2030. infections that may cause cancer, reduc- More than 70% of all cancer deaths occur ing exposure to sunlight, and avoidance of in low and middle income countries. excessive alcohol consumption and stress Five major cancer causing overall mor- (anger). A third of cancers could be cured talities per year worldwide are (WHO): if detected early and treated adequately. It is well established that scientific 1. Lung: 1.

Recenzje

"Once more Professor Hayat has to be congratulated for bringing together 56 leading scientists representing 16 countries in the field of breast cancer, which has made it possible to publish such an excellent book. It represents a valuable addition to the available literature on breast cancer treatment since it covers all aspects of breast cancer, including diagnosis, treatments, and prognosis. Thereby, not only efficacy of various anticancer drugs and their side-effects are pointed out, but also the necessity of age-dependent breast cancer strategies is highlighted. Therefore, I conclude that this book is a true benefit to all clinicians, surgeons, and oncologists working in the field of breast cancer."

Professor Dr. Thomas Dittmer
Institute of Immunology
Witten/Herdecke University
Witten, Germany

"This first volume of the Handbook on Methods of Cancer Diagnosis, Therapy, and Prognosis, concerns problems related to diagnosis, treatment, monitoring of therapy, and prognosis in breast cancer. This is an impressive monograph containing data range on novel techniques (e.g., PET examination of sentinel lymph nodes) used in early diagnosis, prognosis (Molecular studies on circulating neoplastic cells), and treatment (surgery, chemo-radio-and hormontherapy) of various histological types of breast cancer. This monograph resulting from cooperative efforts of 56 authors from 16 countries (specialists in this field) cannot be matched by any publication of this type. The oncologists, pathologists, and scientists engaged in problems of breast cancer should have this extremely valuable Handbook at hand."

Professor Piotr Dziegiel
Department of Histology and Embryology
Medical University of Wroclaw, Poland

"It has been a great pleasure to review the forthcoming book, Methods of Cancer Diagnosis, Therapy, and Prognosis: Volume 1, edited by Professor M.A. Hayat. Dr. Hayat is a Distinguished Professor in the Department of Biological Sciences, Kean University, Union, New Jersey. After seeing the chapters listed in his book, I am very impressed by the thoroughness of the topics in the proposed book. As an editor, Dr. Hayat has assembled a group of well known researchers and clinicians from many parts of the world to write the state-of-the art chapters on breast cancer, including but not limited to the chapters, on computer-assisted diagnosis, familial breast cancer, serum markers in diagnosis, circulating cancer cells before and after treatments, epigenetic markers, metastasis and its detection, validation of biomarkers, immunohistochemistry, invasive cancer and treatments. He has summarized the problems associated with the complexities of research publications which are not easy reading even for many scientists and clinicians. The subject matter is, undoubtedly, complex and formidable for many breast cancer patients.

The current consolidated information on breast cancer research is not readily available. The numbers of cancer cases are projected to increase significantly by 2030, especially in low and middle income countries. Even in the advanced countries, there is a population of low and middle income people who do not have access to appropriate diagnosis and treatment. These people suffer from the same problems as those belonging to the low and middle income countries. Dr. Hayat has provided data in his preface showing that some cancers can be reduced by changes in lifestyle and education. His assessment is very timely.

With best wishes and regards to Dr. Hayat."

Akhouri A. Sinha, Ph.D. Professor of Genetics, Cell Biology and Development, The University of Minnesota and Research Scientist at the Veterans Affairs Medical Center, Minneapolis, Minnesota.

"Professor Hayat has done it again! He has edited (METHODS OF CANCER DIAGNOSIS, THERAPY, AND PROGNOSIS, to be published by Springer) a comprehensive treatise on diagnosis, therapy, recurrence, resistance along with risk benefit ratio in cancers with special emphasis on breast cancer. Scientists and clinicians from the world over have contributed the latest advances in their respective areas of expertise. The reader is provided with a whole field view of the state of the art in breast cancer management. This treatise will serve as a must read for oncologists, scientist researchers and students of cancer biology. I look forward to the next series dealing with epidemiology, genetic predisposition and the role of the tumor microenvironment in cancer biology."

Debabrata Banerjee Ph.D
Associate Professor
Medicine and Pharmacology
Cancer Institute of New Jersey, New Brunswick

Spis treści

1. BREAST CANCER: COMPUTER-AIDED DETECTION Bin Zheng INTRODUCTION DEVELOPMENT OF COMPUTER-AIDED DETECTION SCHEMES EVALUATION OF COMPUTER-AIDED DETECTION SCHEME PERFORMANCE APPLICATION OF COMPUTER-AIDED DETECTION SCHEMES TO CLINICAL ENVIRONMENT NEW DEVELOPMENTS IN COMPUTER-AIDED DETECTION RESEARCH REFERENCES 2. SEBACEOUS CARCINOMA OF THE BREAST: CLINICOPATHOLOGIC FEATURES INTRODUCTION METHODS CLINICAL FEATURES PATHOLOGIC FINDINGS DIFFERENTIAL DIAGNOSIS PROGNOSIS AND TREATMENT REFRENCES 3. BREAST CANCER: DETECTION BY IN VIVO IMAGING OF ANGIOGENESIS Tore Bach-Gansmo and Derek Tobin INTRODUCTION ANGIOGENESIS INTEGRINS SCINTIMAMMOGRAPHY TECHNETIUM-LABELED NC100692 INITIAL CLINICAL EXPERIENCE 99mTc-NC100692 IN BREAST CANCER IMPROVEMENTS IN GAMMA CAMERA TECHNOLOGY SUPPLEMENTARY CLINICAL STUDY FUTURE INTEGRIN SCINTIGRAPHY REFERENCES 4. BREAST AND PROSTATE BIOPSIES: USE OF OPTIMIZED HIGH-THROUGHPUT MicroRNA EXPRESSION FOR DIAGNOSIS (METHODOLOGY) Michael D. Mattie and Robert C. Getts INTRODUCTION METHODOLOGY FOR HIGH-THROUGHPUT microRNA PROFILING Purification of microRNA AMPLIFICATION OF LOW MOLECULAR WEIGHT RNA LABELING OF microRNA REFERENCES 5. FAMILIAL BREAST CANCER: DETECTION OF PREVALENT HIGH-RISK EPITHELIAL LESIONS Peter Bult and Nicoline Hoogerbrugge INTRODUCTION MATERIALS METHODS CLASSIFICATION OF PREMALIGNANT LESIONS REFERENCES 6. DIFFERENTIATION BETWEEN BENIGN AND MALIGNANT PAPILLARY LESIONS OF THE BREAST: EXCISIONAL BIOPSY OR STEREOTACTIC VACUUM-ASSISTED BIOPSY (METHODOLOGY) Alice P.Y. Tang, Gary M.K. Tse, and Wynnie W.M. Lam INTRODUCTION RADIOLOGICAL APPEARANCE OF PAPPILARY LESIONS OF THE BREAST PATHOLOGICAL FINDINGS ASSOCIATION OF PAPPILARY LESIONS WITH DUCTAL CARCINOMA FINE NEEDLE ASPIRATION CORE NEEDLE BIOPSY CURRENT ROLE OF EXCISIONAL BIOPSY DIFFICULTY IN PATHOLOGICAL DIFFERENTIATION BETWEEN MALIGNANT AND BENIGN LESIONS AFTER NEEDLE BIOPSY VACCUM-ASSISTED BIOPSY TECHNIQUE OF STEREOTACTIC VACCUM-ASSISTED BIOPSY TECHNIQUE OF ULTRASOUND-GUIDED VACCUM-ASSISTED BIOPSY ADVANTAGES OF DIRECTIONAL VACCUM-ASSISTED DEVICE COMPLICATIONS OF VACCUM ASSISTED BIOPSY CURRENT EXPERIENCE OF VACCUM-ASSISTED BIOPSY AND PERCUTANEOUS CORE BIOPSY IN THE MANAGEMENT OF PAPPILARY LESIONS IS EXCISION BIOPSY NEEDED IN ASSESSING PAPPILARY LESIONS OF THE BREAST ATYPICAL PAPILLOMA/ PAPILLARY LESION WITH ATYPICAL DUCTAL HYPERPLASIA AT VACCUM-ASSISTED BIOPSY BENIGN PAPILLOMA AT VACCUM-ASSISTED BIOPSY REFERENCES 7. MULTICENTRIC BREAST CANCER: SENTINEL NODE BIOPSY AS A DIAGNOSTIC TOOL Michael Knauer, Peter Konstantiniuk, Anton Haid, Etienne Wenzl, Roswitha Köberle-Wührer, Michaela Riegler-Keil, Sabine Pöstlberger, Roland Reitsamer, and Peter Schrenk INTRODUCTION TECHNIQUE OF SENTINEL NODE BIOPSY IN MULTICENTRIC BREAST CANCER Technique of Lymphatic Mapping Histologic Evaluation of Sentinel Nodes Surgical Procedures RESULTS OF THE AUSTRIAN SENTINEL NODE STUDY GROUP Patients and Data Follow-up DISCUSSION Clinical Advantage of Sentinel Node Biopsy in Multicentric Breast Cancer Quality Control of Sentinel Node Biopsy Procedure REFERENCES 8. BREAST CANCER RECURRENCE: ROLE OF SERUM TUMOR MARKERS CEA AND CA 15-3 (METHODOLOGY) Franco Lumachi, Stefano M.M. Basso, and Umberto Basso INTRODUCTION SERUM TUMOR MARKERS AND BREAST CANCER CARCINOEMBRYONIC ANTIGEN CANCER ANTIGEN 15-3 PREDICTION OF RISK OF RECURRENCE AND LOCOREGIONAL RELAPSE MONITORING THE RESPONSE TO THERAPY OF

Blurb

This is the first book that discusses subjects of diagnosis, therapy, therapy assessment, and prognosis of breast cancer in one single volume. 
  
Cancer killed 6.7 million people around the world in 2002 and this figure is expected to rise to 10.1 million in 2020. Approximately, 189,510 new cases of breast cancer were reported in 2007 in the United States, and 40,910 died in the same year. 

Focusing on Breast Carcinoma, this first volume in the series Methods of Cancer Diagnosis, Therapy and Prognosis brings together 56 leading scientists from around the world to deliver a comprehensive treatise on all aspects of breast cancer, including diagnosis, treatments and prognosis. Scientists and clinicians have contributed state of the art chapters on their respective areas of expertise providing the reader a whole field view of breast cancer management. 
 
This fully illustrated volume: 

* Presents a constructive evaluation of commonly used methods for elucidating primary and secondary cancer initiation, progression, relapse, and metastasis. 

* Highlights methods of breast cancer diagnosis and treatment assessment including various imaging modalities such as ultrasound, computed tomography, magnetic resonance imaging, immunohistochemistry and histochemistry. 

* Discusses detailed therapeutic protocols, including both their benefits and side-effects. 

* Discusses examples of breast cancer treatments includingchemotherapy, radiation, chemoradiation, surgery, hormonal - and immunotherapy 

* Details the molecular processes that lead to the development and proliferation of cancer cells 

* Includes recent major advances in cancer diagnosis and therapy assessment 
 
Professor Hayat has summarized the problems associated with the complexities of research publications and has been successful in editinga must-read volume for oncologists, cancer researchers, medical teachers and students of cancer biology.