Metabolomics: Practical Guide to Design and Analysis

ISBN-13: 9781498725262 / Angielski / Twarda / 2019 / 276 str.

Ron Wehrens; Reza M. Salek

Opis

This book covers Metabolomics, the scientific study of the chemical processes of the metabolic system. It is based on a course taught to masters and postgraduate students of bioinformatics and statistics at the European Bioinformatics Institute at Cambridge.

Spis treści

Part I - Setting the stage. What is metabolomics, definitions. Before you start. Measurement technologies. A short review of applications of metabolomics in different fields, to whet the appetite. Part II - Data processing. NMR. MS, same topics as with NMR. LCDAD. Part III - From data to information. A short review of relevant statistical techniques. Statistical analysis for platforms separately. Data fusion. Metabolic networks. Metabolic flux. Part IV- Data sharing. Data storage and accessibility. Data standards and databases of standards. Conclusion - what is next in metabolomics? Where are the bottlenecks in the bioinformatics part?