Metabolic role of menaquinone biosynthesis in Enterococcus faecalis

ISBN-13: 9783330012172 / Angielski / Miękka / 2016 / 128 str.

Michael Yap; Silas Villas-Boas

Opis

The aim of this project was to evaluate the role of quinone biosynthesis through the targeted disruption of a gene encoding an enzyme essential to the menaquinone biosynthesis in E. faecalis. Compared with its wild-type counterpart, menaquinone biosynthesis mutants displayed an approximate 20% increase in sensitivity to hydrogen peroxide which indicates menaquinone biosynthesis may ultimately play a role in the mediation of oxidative stress in E. faecalis.

O autorze

Based in Singapore, Michael is currently pursuing his interest of overlanding and offroading. He holds an MSc in Biological Sciences at the University of Auckland.