Metabolic Pathway Engineering: Analysis and Applications in the Life Sciences

ISBN-13: 9789814877398 / Angielski / Twarda / 2021 / 156 str.

Jean F. Challacombe

Opis

This book reviews studies on metabolism to current cutting-edge research in metabolic systems engineering. It includes examples to illustrate the applications of this technology in bioengineering to create high-performing microbes and plants that produce important natural products, as well as biological processes.

Spis treści

1. Understanding the Biology of Organisms Through Studies of Metabolism 2. Computational Tools and Approaches for Metabolic Network Reconstruction and Modeling 3. Understanding Microbial Communities 4. In silico Identification of Drug and Vaccine Targets Against Human, Animal, and Plant Pathogens 5. Metabolic Engineering 6. Microbiome Engineering 7. The Future of Systems Metabolic Engineering

O autorze

Jean F. Challacombe is senior genomics bioinformatics specialist in the Department of Cellular and Molecular Medicine, University of California San Diego School of Medicine, USA. She holds a BS in pharmacology, a PhD in neuroscience, and equivalent education and experience to a MS in computer science. Dr. Challacombe is an expert of next-generation sequence analysis of metagenomes and metatranscriptomes; metabolic pathway analysis and modeling; proteome analysis; algorithm and software development with various machine learning tools; design, implementation and administration of different database systems; UNIX/Linux/Mac system administration; high-performance, parallel and distributed computing; and web application development. She enjoys using computational methods to solve complex biological problems.