Mesenchymal Stem Cells for the Heart: From Bench to Bedside

ISBN-13: 9783540881490 / Angielski / Twarda / 2009 / 113 str.

Xiaojie Xie

Opis

Stem cell research has the potential to affect the lives of millions of people around the world. This research is now regularly front-page news, and realizing the promise of mesenchymal stem cells for yielding new medical therapies will require us to grapple with more than just scientific uncertainties. "Mesenchymal Stem Cells for the Heart - From Bench to Bedside" presents the cytobiological characteristics of mesenchymal stem cells from the isolation, culture, transmembrane ion currents, migration and differentiation in vitro to the repairing of injured myocardium and tissue reconstruction in vivo, including the results of basic research and the real possibility for treatments and ultimately for cures for cardiac diseases for which adequate therapies do not exist. The book is intended for clinical stem cell researchers in cardiovasology, hematology, cytobiology, molecular biology, cell and tissue engineering, and other related fields. Jian-an Wang, MD, PhD, Professor of Cardiology at Zhejiang University and investigator at Loma Linda University, Southern California, has broad expertise in the molecular and cellular biological processes underlying cardiovascular disease. He has won the Chinese Medical Science and Technology Medal of Honor.

Spis treści

MSCs Isolation and Culture Ex Vivo.- MSCs Identification.- Biological Characteristics of MSCs.- Utilization of MSCs for Repairing Cardiomyocytes.- Current Status of MSCs in Clinical Application.- MSCs as a Vector of Gene Engineering.- Feasibility of MSCs Transplantaion.- Status and Expectation of MSCs Therapy.

O autorze

Jian-an Wang, MD, PhD, Professor of Cardiology at Zhejiang University and investigator at Loma Linda University, U.S., has broad expertise in the molecular and cellular biological processes underlying cardiovascular disease. He has won the Chinese Medical Science and Technology Medal of Honor. He performs cardiac interventional treatment on more than 1000 cases per year, doing percutaneous coronary angiography (PTCA), percutaneous coronary angioplasty, radiofrequency catheterization ablation (RFCA), percutaneous closure of a residual ventricular septal defect (VSD), atrial septal defect (ASD) and patent ductus arteriosus (PDA) with the Amplatzer occluder, etc. He is also the chief editor of Electrocardiology Journal, Chinese editor of Circulation, European Heart Journal and American Heart Association Journals Best Selection, editor of Chinese Emergency Journal, Chinese Practical Medicine Journal, and Chinese Modern Clinical Medicine Journal.