Part I Biological background: An evolutionary view of menopause.- Menopause: the concepts and the biological background.- Primary ovarian insufficiency.- Part II Impact of estrogen depletion on symptoms and quality of life: Clinical symptoms and quality of life (1).- Clinical symptoms and quality of life (2).- The genitourinary syndrome. Vaginal health and microbiota.- Part III: The impact of estrogen depletion on disease susceptibility: Osteoporosis.- Metabolic syndrome.- Other chronic noncommunicable diseases (Cognitive decline, cardiovascular disease, osteoarthritis).- Part IV Management of menopause: Hormone therapy (I): estrogens and progestogens.- Hormone therapy (II): tibolone, the TSEC concept.- The impact of hormone therapy on the clinical features of menopause.- The impact of hormone therapy on health (Osteoporosis, cancer, cardiovascular disease, cognition).- Pharmacological compounds other than hormones: which and when.- Alternative medicine.- Lifestyle: physical activity.- Lifestyle: nutrition.- Part V Menopause in the context of healthy ageing: Frailty and co-morbidities. Frailty in women.- Sarcopenia and dynapenia.- The health challenges at menopause and midlife: sustainability, ICT technology, patient empowerment.
Antonio Cano is Full Professor of Obstetrics and Gynecology at the University of Valencia. His research focuses on Gynecological Endocrinology, particularly on aspects related to health and senescence in women. Antonio has published over 170 papers in journals including for the JCR Science Edition 2011. He has also published some 150 additional papers or chapters in books and has edited 12 books.