Melanoma Research: Genetics, Growth Factors, Metastases, and Antigens

ISBN-13: 9780792308959 / Angielski / Twarda / 1991 / 176 str.

Larry Ed. Nathanson; Larry Nathanson

Opis

Where do you begin to look for a recent, authoritative article on the diagnosis or management of a particular malignancy? The few general oncology text books are generally out of date. Single papers in specialized journal are informative but seldom comprehensive; these are more often preliminary reports on a very limited number of patients. Certain general journals frequently publish good in-depth reviews of cancer topics, and published symposium lectures are often the best overviews available. Unfortunately, these reviews and supplements appear sporadically, and the reader can never be sure when a topic of special interest will be covered. Cancer Treatment and Research is a series of authoritative volumes that aim to meet this need. It is an attempt to establish a critical mass ofoncology literature covering virtually all oncology topics, revised frequently to keep the coverage up to date, and easily available on a single library shelfor by a single personal subscription. We have approached the problem in the following fashion: first, by dividing the oncology literature into specific subdivisions such as lung cancer, genitourinary cancer, pediatric oncology, etc.;and second, by asking eminent authorities in each of these areas to edit a volume on the specific topic on an annual or biannual basis. Each topic and tumor type is covered in a volume appearing frequently and predictably, discussing current diagnosis, staging, markers, all forms of treatment modalities, basic biology, and more."

Spis treści

I. Genetics of Melanoma.- 1. Cytogenetic Analysis in Melanoma and Nevi.- II. Growth Regulation/Oncogenes.- 2. Growth Factors Regulating Normal and Malignant Melanocytes.- 3. Cytokines and Human Malignant Melanoma: Immuno- and Growth-Regulatory Peptides in Melanoma Biology.- 4. Phorbol Esters and Growth Regulation in Metastatic Melanoma Cells.- 5. Regulation of Growth and Phenotype of Normal Human Melanocytes in Culture.- III. Metastases.- 6. Experimental Model of Human Melanoma Metastases.- 7. The Role of Meltalloproteinases in Tumor Cell Metastasis.- IV. Antigens.- 8. Ganglioside Antigens in Tissue Sections of Skin, Naevi, and Melanoma: Implications for Treatment of Melanoma.- 9. Modulation of Melanoma Antigens by Interferons.