Medicinal Protein Engineering

ISBN-13: 9780849373688 / Angielski / Twarda / 2008 / 586 str.

Khudyakov E. Khudyakov; Yury E. Khudyakov; Yury E. Khudyakov

Opis

Protein engineering is a molecular biological discipline focused on designing and constructing novel proteins with desired properties. This title discusses computational approaches to protein design and experimental approaches to protein construction. It also explores the tight connection between protein and genetic engineering.

Spis treści

Computational Approaches. Web Resources for Protein Analysis. Artificial Neural Networks for Therapeutic Protein Engineering. Phylogenetics and Medicinal Protein Engineering. Clustering and Classification Approaches to Identifying Protein Properties. Analysis of Coordinated Substitutions in Proteins. Protein Engineering Targets: Vaccine. Tuning the Immune Response to Our Advantage: Design of Vaccines with Tailored Functions. Modification of HIV-1 Envelope Glycoprotein to Enhance Immunogenicity. Engineering Better Influenza Vaccines: Traditional and New Approaches. Construction of Novel Vaccines on the Basis of Virus-Like Particles: Hepatitis B Virus Proteins as Vaccine Carriers. Polyomavirus-Derived Virus-Like Particles. Papillomavirus-Derived Virus-Like Particles. Recombinant Vaccines Against Hepatitis Viruses. Protein Engineering Targets: Diagnostics and Therapy. Designer Diagnostic Reagents and Allergens. Peptide-Based Diagnostic Assays. Recombinant Antibodies. Protein Engineering for HIV Therapeutics. Recombinant Enzymes with New and Improved Properties. Special Expression Systems. Production of Pharmaceutical Compounds in Plants. Plant Virus Biotechnology Platforms for Expression of Medicinal Proteins. Alphaviruses: Multiplicity of Vectors and Their Promising Application as Vaccines and Cancer Therapy Agents. Index.

O autorze

Khudyakov, Yury E.