Mechanochemistry and Emerging Technologies for Sustainable Chemical Manufacturing

ISBN-13: 9780367775018 / Angielski

Evelina Colacino; Felipe Garcia

Opis

This unique volume describes advances in the field of mechanochemistry, in particular the scaling up of mechanochemical processes. Scalable techniques employed to carry out solvent-free synthesis are evaluated. Comparability to continuous flow chemistry, the current industrial benchmark for continuous efficient chemical synthesis, is presented.The book concludes that mechanochemical synthesis can be scaled up into a continuous, sustainable process. It demonstrates that large scale mechanochemistry can meet industrial demands especially in the pharmaceutical industry. The case studies conducted on MOF Technologies and Deasyl demonstrate how mechanochemistry is employed on a pilot plant scale.

Features

• Mechanochemistry is rapidly developing as a multidisciplinary science on the borderline between chemistry, materials science and environmental science.
• This unique text focuses on mechanochemistry with the ability to scale up and illustrates how mechanochemical synthesis is no longer an obstacle.
• Timely and highlights recent advancements describing what can be achieved in chemical synthesis.
  
• Mechanochemistry enables the synthesis of multiple polymorphic crystalline forms in the production of drugs in the form of tablets or granules in capsules.
  
• The case studies conducted on MOF Technologies and Deasyl demonstrate how mechanochemistry is employed on a pilot plant scale.