Mechanisms of Morphogenesis

ISBN-13: 9780323999656 / Angielski / Miękka / 2023

UK) Davies Jamie A. (University of Edinburgh

Spis treści

Section I: Introduction 1. General introduction - the aims and structure of this book. 2. Key principles of morphogenesis 3. The power and limitations of self-assembly

Section II: Cell shape and the cell morphogenesis 4. Morphogenesis of individual cells 5. Animal cell shape: the importance of the cytoskeleton 6. Cellular morphogenesis in plants

Section III: Cell Migration 7. Cell migration in development: a brief overview 8. The nanomachinery of locomotion 9. Guidance by chemotaxis 10. Guidance by galvanotaxis 11. Guidance by contact 12. Waypoint navigation in the embryo 13. Cooperative migration of mesenchymal cells 14. Condensation of cells

Section IV: Epithelial Morphogenesis 15. The epithelial state: a brief overview 16. Neighbour exchange and convergent extension 17. Closure of holes 18. Invagination and evagination 19. Epithelial fusion 20. Epithelial branching 21. Boundaries to epithelial movement

Section V: Morphogenesis by cell proliferation and death 22. Growth, proliferation and death: a brief overview 23. Morphogenesis by orientated cell division 24. Morphogenesis by elective cell death

Section VI: Morphogenesis in context 25. From mechanisms to morphology: a brief overview 26. Morphogenesis in embryos: some illustrative examples 27. Morphogenesis in organoids, embryoids and engineered tissues 28. Pathological morphogenesis

Section VII: Modelling morphogenesis 29. Modelling morphogenesis: a brief overview 30. Mechanical and mathematical models of morphogenesis 31. Modelling using living cells - tissue engineering and synthetic morphology

Section VIII: Conclusion and perspectives 32. Conclusion and perspectives