Mechanics of Biomaterials

ISBN-13: 9780521762212 / Angielski / Twarda / 2011 / 698 str.

Lisa A Pruitt

Opis

Teaching mechanical and structural biomaterials concepts for successful medical implant design, this self-contained text provides a complete grounding for students and newcomers to the field. Split into three sections: Materials, Mechanics and Case Studies, it begins with a review of sterilization, biocompatibility and foreign body response before presenting the fundamental structures of synthetic biomaterials and natural tissues. Mechanical behavior of materials is then discussed in depth, covering elastic deformation, viscoelasticity and time-dependent behavior, multiaxial loading and complex stress states, yielding and failure theories, and fracture mechanics. The final section on clinical aspects of medical devices provides crucial information on FDA regulatory issues and presents case studies in four key clinical areas: orthopedics, cardiovascular devices, dentistry and soft tissue implants. Each chapter ends with a list of topical questions, making this an ideal course textbook for senior undergraduate and graduate students, and also a self-study tool for engineers, scientists and clinicians.

Recenzje

'Mechanics of Biomaterials: Fundamental Principles for Implant Design provides a much needed comprehensive resource for engineers, physicians, and implant designers at every level of training and practice. The book includes a historical background which outlines the engineering basis of traditional implant designs, and interactions of materials, biology, and mechanics resulting in clinical success or failure of these devices. Each chapter contains a detailed description of the engineering principles which are critical to understand the mechanical behavior of biomaterials and implants in vivo. The scope of the text covers orthopaedics, cardiovascular devices, dental, and soft tissue implants, and should help considerably in our efforts to improve the function and durability of biomaterials and implants used in clinical practice.' Michael Ries, University of California, San Francisco

Spis treści

Part I. Materials: 1. Biocompatibility, sterilization and materials selection for implant design; 2. Metals for medical implants; 3. Ceramics; 4. Polymers; 5. Mechanical behavior of structural tissues; Part II. Mechanics: 6. Elasticity; 7. Viscoelasticity; 8. Failure theories; 9. Fracture mechanics; 10. Fatigue; 11. Friction, lubrication and wear; Part III. Case Studies: 12. Regulatory affairs and testing; 13. Orthopedics; 14. Cardiovascular devices; 15. Oral and maxillofacial devices; 16. Soft tissue replacements; Appendix A. Selected topics from mechanics of materials; Appendix B. Table of material properties of engineering biomaterials and tissues; Appendix C. Teaching methodologies in biomaterials; Glossary; List of symbols.