Matrix Metalloproteinases and Periodontal Disease

ISBN-13: 9786204725154 / Angielski / Miękka / 72 str.

Shikha Sharma; Shobha Prakash

Opis

The disease progression involves a network of interacting molecular pathways made of pro-inflammatory mediators like cytokines, growth factors, reactive oxygen species,matrix metalloproteinases (MMPs), and their inhibitors and regulators. Matrix macromolecules like proteoglycan and non- ollagen protein can be degraded by proteinases from the four major classes (metallo, serine, cysteine, and aspartic active site residues). Matrix metalloproteinases (MMPs) are members of a large subfamily of Zn 2+ and Ca 2+ dependent proteolytic enzymes, playinganimportant role in periodontal destruction.

O autorze

Sharma, ShikhaDr. Shikha Sharma, currently associated with SGT university as Assistant Professor. She has completed her BDS from MCODS, Manipal and Post Graduation from College of dental sciences, Davangere. The author has in her account both national and international publications.