Mass-Action Law Dynamics Theory and Algorithm for Translational and Precision Medicine Informatics

ISBN-13: 9780443288746 / Miękka / 2024 / 200 str.

Ting-Chao (PD Science LLC) Chou

Spis treści

1. Introduction and Overview
2. Experimental and clinical trial protocol design and data analysis: Two Opposite yet complementary alternatives toward the goals of R&D
3. MAL-PD/CI approach for biomedical R&D in vitro and in animals
4. Implementation for MAL-PD Econo-Green R&D
5. Current Landscape of International FDA Drug Evaluation, Clinical Pharmacology, and Clinical Trials Guidance
6. The epothilone story: Experimental success and clinical failure
7. MAL-PD Advocacy: Public Hearing, Public Comments and Scientific Recommendations
8. Consensus from international FDAs on Definitions of "MAL-PD” and "Synergism”
9. Why MAL-PD Approach and the Traditional Approach are Opposite yet Complementary
10. Summary and examples of applications: Papers Using the MAL-PD/BD/CI/BI theory/method..
11. Conclusions