Markers in Cardiology: A Case-Oriented Approach

ISBN-13: 9781405134187 / Angielski / Twarda / 2007 / 272 str.

Fred S. Apple; Allan Jaffe; Jesse Adams

Opis

The correct application of protein markers to patients with cardiac disease is critical for optimal diagnosis and treatment. This text presents an in-depth analysis of the measured levels of diverse proteins (markers) that can detect cardiac injury. It covers technical, clinical and outcome assessments for each marker used in clinical practice.

Recenzje

"I think this is a good book and good value for money. It is fairly light reading and I found myself wanting to make notes and use it as a point of reference as it pulls things together well. Therefore, I would recommend it to others." ( Cardiology News, February 2009)

Spis treści

Contents.

Contributors.

Preface.

Part 1 Cardiac troponins.

1 Basics of cardiac troponin: practical aspects of assays, potential.

analytical confounders, and clinical interpretation.

Fred S. Apple (University of Minnesota School of Medicine).

2 Diagnostic use of cardiac troponins in ST–segment elevation.

myocardial infarction.

Susanne Korff (Medizinische Universitätsklinik Heidelberg), Hugo A. Katus (Department of Cardiology), Evangelos Giannitsis (Department of Cardiology).

3 Therapeutic implications of cardiac troponins in ST–segment.

elevation and non–ST–segment elevation myocardial.

infarction.

Tracy Y. Wang, John M. Castor, L. Kristin Newby.

4 Ischemic heart disease in the absence of overt coronary.

artery disease.

Allan S. Jaffe (Mayo Clinic).

5 So you think you have a false positive troponin?.

Jesse E. Adams (Jewish Hospital Heart and Lung Institute).

6 Use of cardiac troponin in patients in non–ischemic pathologies.

and exposure to environmental toxins.

Fred S. Apple (University of Minnesota School of Medicine).

7 Cardiac troponins in patients with congestive heart failure.

Jesse Adams (Jewish Hospital Heart and Lung Institute).

8 Troponins and the critically Ill patient.

Jose Antonio Perez (Mayo Clinic & Medical School), Luciano Babuin (Cardiovascular Division & Cardiovascular), Allan S. Jaffe (Mayo Clinic).

9 Cardiac troponins and renal failure.

Suresh Pothuru (University of Maryland), Christopher deFilippi (University of Maryland).

10 Cardiac biomarkers: detection of in–hospital myocardial.

reinfarction.

Fred S. Apple (University of Minnesota School of Medicine).

Part 2 Natriuretic peptides.

11 The future: interpreting new guidelines for myocardial.

infarction.

Allan S. Jaffe (Mayo Clinic).

12 Basics of natriuretic peptides: practical aspects of assays,.

potential analytical confounders, and clinical interpretation.

Alan H.B. Wu (San Francisco General Hospital).

13 Natriruetic peptides in clinical practice.

Alan Maisel (University of California).

14 Outpatient evaluation for cardiovascular diseases using.

natriuretic peptide testing.

Aaron L. Baggish (Massachusetts General Hospital), James L. Januzzi (Harvard Medical School).

15 Natriuretic peptides in patients with renal failure.

Peter A. McCullough (William Beaumont Hospital).

16 Congestive heart failure: treatment implications of natriuretic.

peptides.

W Frank Peacock (Emergency Cardiology Research).

17 Utilizing multimarker strategies in patients who present with.

congestive heart failure.

Johannes Mair (Universitaetsklinik fuer Innere Medizin).

Part 3 Contemporary markers of risk.

18 Clinical integration of C–reactive protein for primary and.

secondary risk factor stratification.

Jesse E. Adams (Jewish Hospital Heart and Lung Institute).

19 Lipoprotein subfraction analysis using nuclear magnetic.

resonance spectroscopy.

William C. Cromwell (Presbyterian Center for Preventive Cardiology), Harold E. Bays (L–Marc Research Center), Peter P. Toth (Director of Preventive Cardiology).

Index

O autorze

Jesse E. Adams, MD FACC
University of Louisville
Division of Cardiology
100 Mallard Creek
Louisville, KY 40202
USA

Fred Apple, PhD
Department of Laboratory Medicine and Pathology
Hennepin County Medical Center and University of Minnesota School of Medicine
Minneapolis, MN
USA

Allan S. Jaffe, MD
Cardiovascular Division and Cardiovascular Research Institute and Division of Laboratory Medicine
Mayo Clinic and Medical School
Rochester, Minnesota
USA

Blurb

With the rapid development of the field of cardiac biomarkers comes a need for updated guidance on how to use them clinically. Drs. Adams, Jaffe, and Apple meet that need with this timely reference.

Taking a case–oriented approach for the greatest clinical relevance, the book bridges the gap between science and practice. If you use or want to use cardiac markers such as BNP and troponin to help your patients, you will find this clear and comprehensive reference provides a dependable source of valuable information.

The 19 chapters are divided into three parts:

Cardiac Troponins
Natriuretic Peptides
Contemporary Markers of Risk

The authors cover the technical, clinical, and outcome assessments for each marker used in clinical practice. After each case scenario, an extensive discussion explains the clinical decisions and provides valuable context.