Marine Enzymes and Specialized Metabolism - Part a: Volume 604

ISBN-13: 9780128139592 / Angielski / Twarda / 2018 / 556 str.

Bradley S. Moore

Spis treści

Section I: Marine Cyanobacteria, Enzymes and Pathways 1. Collection, Culturing, and Genome Analyses of Tropical Marine Filamentous Benthic Cyanobacteria Nathan A. Moss, Tiago Leao, Evgenia Glukhov, Lena Gerwick and William H. Gerwick 2. PKS-NRPS Enzymology and Structural Biology: Considerations in Protein Production Meredith A. Skiba, Finn P. Maloney, Qingyun Dan, Amy E. Fraley, Courtney C. Aldrich, Janet L. Smith and W. Clay Brown 3. Terminal Alkyne Biosynthesis in Marine Microbes Xuejun Zhu and Wenjun Zhang 4. The Biochemistry and Structural Biology of Cyanobactin Biosynthetic Enzymes Wenjia Gu, Shi-Hui Dong, Snigdha Sarkar, Satish K. Nair and Eric W. Schmidt 5. The Enzymology of Prochlorosin Biosynthesis Silvia C. Bobeica and Wilfred A. van der Donk

Section II: Biosynthesis by Bacterial Symbionts of Marine Invertebrate Animals 6. Chemoenzymatic Dissection of Polyketide ß-Branching in the Bryostatin Pathway Samuel T. Slocum, Andrew N. Lowell, Ashootosh N. Tripathi, Vikram V. Shende, Janet L. Smith and David H. Sherman 7. Radical S-Adenosylmethionine Peptide Epimerases: Detection of Activity and Characterization of d-Amino Acid Products Brandon I. Morinaka, Anna L. Vagstad and Jörn Piel 8. Cobalamin-Dependent C-Methyltransferases From Marine Microbes: Accessibility via Rhizobia Expression Michael F. Freeman 9. Biosynthetic Insights of Calyculin- and Misakinolide-Type Compounds in "Candidatus Entotheonella sp." Agustinus R. Uria, Jörn Piel and Toshiyuki Wakimoto

Section III: Natural Product Biosynthetic Enzymology of Marine Bacteria and Fungi 10. Chemoenzymatic Synthesis of Starting Materials and Characterization of Halogenases Requiring Acyl Carrier Protein-Tethered Substrates Hem R. Thapa, Andrew J. Lail, Neha Garg and Vinayak Agarwal 11. Preparation, Assay, and Application of Chlorinase SalL for the Chemoenzymatic Synthesis of S-Adenosyl-L-Methionine and Analogs Tony D. Davis, Sylvia Kunakom, Michael D. Burkart and Alessandra S. Eustaquio 12. In Vitro Analysis of Cyanobacterial Nonheme Iron-Dependent Aliphatic Halogenases WelO5 and AmbO5 Xinyu Liu 13. Characterization and Biochemical Assays of Streptomyces Vanadium-Dependent Chloroperoxidases Shaun M.K. McKinnie, Zachary D. Miles and Bradley S. Moore 14. Unusual "Head-to-Torso" Coupling of Terpene Precursors as a New Strategy for the Structural Diversification of Natural Products Robin Teufel 15. Identification of Enzymes Involved in Sesterterpene Biosynthesis in Marine Fungi Jingjing Yan, Jingjing Guo, Wei Yuan, Wanying Mai and Kui Hong 16. Assaying Oxidative Coupling Activity of CYP450 Enzymes Vinayak Agarwal 17. Preparation and Characterization of the Favorskiiase Flavoprotein EncM and Its Distinctive Flavin-N5-Oxide Cofactor Robin Teufel

O autorze

Bradley S. Moore is a Professor at the Scripps Institution of Oceanography, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego.