Mapping of Nervous System Diseases via MicroRNAs

ISBN-13: 9780367871154 / Angielski / Miękka / 2019 / 262 str.

Christian Barbato; Francesca Ruberti

Opis

This book provides an up-to-date review of the function of microRNA (miRNA) in neurological diseases as well as advancements in technology for therapeutic modulation of miRNA activity. It covers general concepts and novel insights on brain function in relation to miRNA and also examines the role of miRNAs in various neurological diseases. Coveri

Spis treści

MicroRNAs IN THE NERVOUS SYSTEM AND NEUROLOGICAL DISEASES (BASIC): MicroRNAs IN THE NERVOUS SYSTEM. MicroRNA Biology and Function in Nervous System. MicroRNAs IN THE NERVOUS SYSTEM AND NEUROLOGICAL DISEASES (BASIC): MicroRNAs IN NEUROPSYCHIATRIC DISEASES. MicroRNAs in Mood and Anxiety Disorders. MicroRNA Dysregulation in Schizophrenia and Functional Consequences. The Impact of MicroRNAs in Synaptic Plasticity, Major Affective Disorders, and Suicidal Behavior. MicroRNAs IN THE NERVOUS SYSTEM AND NEUROLOGICAL DISEASES (BASIC): MicroRNAs IN NEUROLOGICAL DISEASES. MicroRNAs in Prion Diseases. MicroRNAs in Epileptogenesis and Epilepsy. MicroRNAs and Pain. MicroRNA BIOMARKERS IN NEUROLOGICAL DISEASES (APPLICATIONS). Circulating Cell-Free MicroRNAs as Biomarkers for Neurodegenerative Diseases. Circulating Cell-Free MicroRNAs as Biomarkers for Neural Development and Its Importance in Fetal Programming for Postnatal Disease.

O autorze

Christian Barbato, MD, is a researcher at the Institute of Cell Biology and Neurobiology, CNR, in Italy. He earned his PhD in neuroscience from the University of Rome Tor Vergata, Italy. His past work has focused on the characterization of cellular and molecular neurobiology of RNA-induced silencing complex and noncoding RNA in synaptic plasticity, learning, and memory. His recent research focuses on the function of microRNAs and their gene targets implicated in physiological and pathological processes of neurons.

Francesca Ruberti, PhD, is a researcher at the Institute of Cell Biology and Neurobiology, CNR, in Italy. He earned his PhD in biophysics from the International School of Advanced Studies, Trieste, Italy. His past research has focused on the role of nerve growth factor on specific neuronal populations of the central nervous system and on synaptic plasticity in the hippocampus, and on the molecular mechanisms involved in the cellular localization of specific neuronal proteins or messenger RNAs. His recent research focuses on the study of microRNAs and their gene targets implicated in physiological and pathological processes of neurons.