Managing Brca Mutation Carriers

ISBN-13: 9783319591971 / Angielski / Twarda / 2017 / 242 str.

Anees Chagpar

Opis

As there are a number of nuances in terms of how to manage mutation carriers (both with and without a concomitant diagnosis of breast cancer), this text provides a comprehensive, state-of-the art review of this field. It represents a valuable resource for a myriad of clinicians and healthcare personnel who interface with these patients. The text discusses the latest recommendations for genetic counseling and risk assessment, provides a framework for considering reducing risk in mutation carriers who do not present with a concomitant diagnosis of breast cancer, and finally elucidates the many considerations of managing a breast cancer patient with a BRCA mutation. The text presents a multidisciplinary approach gleaning insights from imaging, breast surgery, gynecology, plastic surgery, medical oncology, radiation oncology and psycho-oncology.

Managing BRCA Mutation Carriers will be a useful resource for physicians and healthcare providers from a myriad of disciplines who manage BRCA mutation carriers. All chapters are written by experts in their fields and include the most up to date scientific and clinical information.

Spis treści

Managing BRCA Mutation Carriers

Anees B. Chagpar

Contents

Preface

 Chapters

1 Risk Assessment for Breast Cancer

Anvy Nguyen, Jessica Cintolo-Gonzalez, Jennifer K. Plichta, and Kevin S. Hughes

 2 Genetic Evaluation for Women at Increased Risk

Karina L. Brierley, Claire L. Healy, and Erin W. Hofstatter

 3 Imaging Screening and Surveillance

Ellen Warner

 4 Risk Reducing Surgery for BRCA1/2 Genetic Mutation Carriers

Cristina O’Donoghue, Sonia Orcutt, Tuya Pal, and Christine Laronga

 5 Prophylactic Oophorectomy for Patients with Germline BRCA Mutations

Dario R. Roque and Don S. Dizon

 6 Pathology of BRCA Tumors

Julio A. Ibarra

 7 Surgical Management of Breast Cancer in BRCA Mutation Carriers

Patricia A. Cronin and Hiram S. Cody III

 8 Medical Management of Breast Cancer in BRCA Mutation Carriers

Soley Bayraktar and Banu K. Arun

 9 Radiation Oncology Considerations in the Management of Mutation Carriers with Breast Cancer

Meena S. Moran

 10 Fertility Preservation in BRCA Carriers: Special Considerations

Iris G. Insogna, Elizabeth S. Ginsburg and Ann H. Partridge

 11 Management of Male BRCA Mutation Carriers

Donna-Marie Manasseh, Ryland J. Gore and Patrick I. Borgen

 12 Psychosocial, Ethical and Legal Implications for Mutation Carriers

Jacquelyn M. Powers, Jessica M. Long and Willonie Mendonca

O autorze

Anees B. Chagpar, MD, MSc, MPH, MA, MBA, FRCS(C), FACS

Associate Professor, Department of Surgery

Director, The Breast Center -- Smilow Cancer Hospital at Yale-New Haven

Assistant Director -- Global Oncology, Yale Comprehensive Cancer Center

Yale University School of Medicine

20 York Street, First floor Suite A

New Haven, CT 06510

Phone:  203-200-1518