Mammalian Transient Receptor Potential (TRP) Cation Channels: Volume I

ISBN-13: 9783642542145 / Angielski / Twarda / 2014 / 726 str.

Bernd Nilius;Veit Flockerzi

Opis

In this fast moving field the main goal of this volume is to provide up-to-date information on the molecular and functional properties and pharmacology of mammalian TRP channels. Leading experts in the field will describe properties of a single TRP protein/channel or portray more general principles of TRP function and important pathological situations linked to mutations of TRP genes or their altered expression. Thereby this volume on Transient Receptor Potential (TRP) Channels provides valuable information for readers with different expectations and backgrounds, for those who are approaching this field of research as well as for those wanting to make a trip to TRPs.

Spis treści

TRPs -Truly Remarkable Proteins.- The TRCP Subfamily: TRPC1.- TRPC2.- TRPC3- a Multifunctional Signaling Molecule.- TRPC4 and TRPC4-Containing Channels.- TRPC5.- TRPC6: Physiological Function and Pathophysiological Relevance.- Transient Receptor Potential Canonical 7 (TRPC7).- The TRPV Subfamily: TRPV1.- TRPV2.- TRPV3.- The TRPV4 Channel.- TRPV5, a Ca2+ Channel for the Fine Tuning of Ca2+ Reabsorption.- TRPV6 Channels.- The TRPM Subfamily: TRPM1.- TRPM2.- TRPM3.-TRPM4.- TRPM5.- TRPM6.- TRPM7.- TRPM8.- The TRPA1, TRPML and TRPP Subfamily: TRPA1.- TRPML1: An Ion Channel in the Lysosome.- TRPML2 and Mucolipin Evolution.- TRPML3.- TRPP Subfamily and Polycystin-1 Proteins.