Malignant Mesothelioma and Pseudomyxoma

ISBN-13: 9783319995090 / Angielski / Twarda / 2019 / 121 str.

Mikhail Kiselevsky; Amir Abdullaev; Mikhail Davydov

Spis treści

Preface

1. Mesothelioma and pseudomyxoma peritonei: incidence, etiology, diagnosis

2. Pathology of selected primary and metastatic tumors of peritoneum

3. Treatment of patients with pseudomyxoma peritonei and peritoneal mesothelioma

4. Standardizing of mesothelioma and pseudomyxoma care

5. Experimental substantiation of optimal regimes of hyperthermic peritoneal chemotherapy

6. Immunotherapy of malignant  peritoneal mesothelioma and pseudomixoma peritonei

Index

O autorze

Prof. Mikhail V Kiselevskiy, Head of Laboratory of Cell Immunity of NN Blokhin  Russian Cancer Research Center. Adoptive immunotherapy of cancer,  Honored Scientist of the Russian Federation and Laureate of the Prize of Russian Government. Professional interests - adoptive immunotherapy of cancer and investigation of mechanisms of anticancer immunity.

Dr Amir G  Abdullaev, Oncologist and surgeon  at Thoracic Research Department, NN Blokhin Russian Cancer Research Center and Assistant Professor of Department of Oncology, Sechenov Medical University. Professional interests - cytoreductive surgery  and hyperthermic intraperitoneal chemotherapy of mesothelioma and pseudomyxoma

 Dr Mikhail  M Davydov,  member of Russian Academy of Sciences, Head of Thoracic Research Department, NN Blokhin Russian Cancer Research Center and Head  of Department of Oncology, Sechenov Medical University. Professional interests - thoracic and abdominal surgery of malignant tumors. 

Blurb

This book covers different aspects of the rare neoplasms – malignant mesothelioma and pseudomyxoma peritonei. The monograph includes up-to-date information on etiology, pathogenesis and diagnostics of malignant mesothelioma and pseudomyxoma peritonei, as well as detailed description of surgical and combined treatment of patients with these diseases. The book comprises a large illustrative material presented by schemes and original micrographs that represent pathological and immunohistochemical specific features of these malignancies, demonstrate the stages of surgical operations and hyperthermic intraperitoneal chemotherapy, and show the results of experimental studies. 

The book includes validated discussion on etiology and pathogenesis of malignant mesothelioma and pseudomyxoma peritonei, differential diagnosis and treatment of these diseases. The scope is really extensive and involves, for instance, a description of the technique of cytoreductive surgeries and regimens of intraperitoneal hyperthermic chemoperfusion, whereas a particular section discusses experimental ground for optimal regimens of hyperthermia, local chemotherapy and adoptive immunotherapy by cytokine induced killers. The final section presents the most recent data about perspective approaches for immunotherapy of malignant mesothelioma and pseudomyxoma peritonei with cell based technologies and target drugs including inhibitors of immune checkpoints. The co-authors of the book are leading specialists in this area, surgeons and scientists who present the results of their research along with the analysis of the state-of-the-art of this problem.

The book is designed for a wide audience of students and professors of medical universities and schools, specialists of research and diagnostic centers, practical oncologists and immunologists, as well as doctors of different medical areas.