Maldi-Tof Mass Spectrometry of Synthetic Polymers

ISBN-13: 9783540442592 / Angielski / Twarda / 2003 / 300 str.

Gerd H. Theissen; Harald Pasch; Wolfgang Schrepp

Opis

MALDI-TOF mass spectrometry is one of the latest and most fascinating new developments in the analysis of organic compounds. Originally developed for the analysis of biomolecules, it has developed into one of the most powerful techniques for the characterization of synthetic polymers. This book describes the fundamentals of the MALDI process and the technical features of MALDI-TOF instrumentation. It reviews the application of MALDI-TOF for identification, chemical and molar mass analysis of synthetic polymers. With many examples, this monograph examines in detail experimental protocols for the determination of endgroups, the analysis of copolymers and additives, and the coupling of liquid chromatography and MALDI-TOF.

Recenzje

From the reviews:

First of all, I like the book. The outline is very good to start with introductury material and then to provide details about different polymer-MALDI studies. You have included many examples. So, in summary, I think the book is great and will be a significant contribution. (David M. Hercules, Centennial Professor and Chair, Department of Chemistry, Vanderbilt University, Nashville, Tn)

From "Journal of the American Chemical Society", Vol. 125/51, 2003:
"... All major applications of MALDI-TOF in polymer analysis, including determination of molar mass and analysis of functional groups and copolymers, are presented, and useful information about instrumentation, selection of matrices, and experimental conditions is provided. ... In general, the book is well written and provides comprehensive information toward practical and established MALDI-TOF MS of synthetic polymers. Other newly developed areas, such as the analysis of nanoparticles, are only mentioned in passing, however. Nonetheless, the book is recommended reading for practitioners in this field."

In general, the book is well written and provides comprehensive information toward practical and established MALDI-TOF MS of synthetic polymers. Other newly developed areas, such as the analysis of nanoparticles, are only mentioned in passing, however. Nonetheless, the book is recommended reading for practitioners in this field.
Mehdi Moini, University of Texas at Austin
Journal of the American Chemical Society, Vol. 125

"The book provides a wealth of useful information from a large number of references and is highly recommended to polymer mass spectrometrists and polymer chemists ... . The book is well written and useful both to polymer chemists who want to learn about mass spectrometry's capabilities and to mass spectrometrists who seek a better understanding of the MALDI method and the advantages of MS with chromatographic combining separation." (Chrys Wesdemiotis, Analytical and Bioanalytical Chemistry, Vol. 381, 2005)

"This book offers a summary of the fundamentals and the technical aspects of the matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS) of synthetic polymers as well as detailed experimental procedures. ... the book is well written and provides comprehensive information toward practical and established MALDI-TOF MS of synthetic polymers. ... is recommended reading for practitioners in this field." (Mehdi Moini, Journal of the American Chemical Society, Vol. 125 (51), 2003)

Spis treści

1 Introduction.- 2 Mass Spectrometric Instrumentation.- 3 Fundamentals of MALDI-TOF Mass Spectrometry.- 4 Identification of Polmers.- 5 Molar Mass Determination.- 6 Analysis of Complex Polymers.- 7 COUPLING OF LIQUID CHROMATOGRAPHY AND MALDI-TOF Mass Spectromety.- 8 Recent Developments and Outlook.- 9 Subject Index.

Blurb

 

MALDI-TOF mass spectrometry is one of the latest and most fascinating new

developments in the analysis of organic compounds. Originally developed for

the analysis of biomolecules, it has developed into one of the most powerful

techniques for the characterization of synthetic polymers. This book

describes the fundamentals of the MALDI process and the technical features

of MALDI-TOF instrumentation. It reviews the application of MALDI-TOF for

identification, chemical and molar mass analysis of synthetic polymers.

Experimental protocols for the determination of endgroups, the analysis of

homo- and copolymers, and the coupling of liquid chromatography and

MALDI-TOF are discussed in detail.