Macrophages and Lymphocytes: Nature, Functions, and Interaction

ISBN-13: 9781468435955 / Angielski / Miękka / 2012 / 634 str.

M. R. Escobar; M. R. Escobar

Opis

The Reticuloendothelial (RE) Society, which is concerned with advd cement of knowledge concerning the many diverse functions of RE cells, organizes national and international meetings and publishes a scientific journal. The VIII International Congress of the RE Society was held in Jerusalem, Israel, June 18-23, 1978. The Congress had as its scientific objec, tive a wide range of sub- jects concerning the RE System, especially as related to macro- phage function and interaction with lymphocytes. Emphasis of the Congress was placed on the nature and function of macrophages and other cells of the RE System with reference to immune responses, anti-infectious activity, tumor immunity, autoimmunity, and trans- plant rejection. The secretion of soluble factors by rnacrophages and lymphocytes and the mode of action of these factors on other cells was stressed. During the Congress some discussion was entertained concerning the controversy as to what constitutes the "RE System" per se. Some investigators feel that the phagocytic activity of rnacrophages is the most important aspect of the RE System playing also a major role in many parameters of immunity. Mononuclear phagocytes include tissue rnacrophages as well as cir- culating monocytes and their precursors. Although phagocytosis is a major functional activity of these cells, it is only one of several activities.

Spis treści

of Part A.- Section 1 Enzymatic and Metabolic Activities of the Reticuloendothelial System.- Association of Some Metabolic Activities of Leukocytes with the Immune Response.- Role of the RES in Lead Salt Sensitization to Endotoxin Shock.- A Metabolic Comparison Between Human Blood Monocytes and Neutrophils.- The Regulation of Macrophage Activities: Role of the Energy-Dependent Intracellular Ca2+ Buffering Systems.- O2? and H2O2 Production During the Respiratory Burst in Alveolar Macrophages.- Biochemical and Biological Properties of Leukocyte Intracellular Inhibitors of Proteinases.- Immunological Studies of Intracellular Leukocyte Proteinase Inhibitor by Granular Extract and Cathepsin D.- A Comparative Study of the Biochemical Properties of Myeloperoxidase and Eosinophil Peroxidase.- Glucocorticoid Protection of Hepatic Phagocytosis in Hypoxia.- Evidence that Phagocytosing Chicken Polymorphonuclear Leukocytes Generate Hydrogen Peroxide and Superoxide Anion.- The Role of Leukocyte Extracts and Myeloperoxidase in the Lysis of Staphylococci and the Inhibition of Bacteriolysis by Anionic Polyelectrolytes and by Inflammatory Exudates.- Biological and Biochemical Characteristics of the Tetrapeptide Tuftsin, Thr-Lsy-Pro-Arg.- Angiotensin Converting Enzyme: Induction in Rabbit Alveolar Macrophages and Human Monocytes in Culture.- Effect of Proteinases on EA (IgG)-Binding Receptors of Rat Macrophages.- Endotoxin-Induced SAA Elevation in the Mouse — Lack of A Role For Complement or Acid Proteases.- Differential Effect of Polycations on Uptake and Desulphation of Heparin.- The Purification of Plasma Membranes from Guinea Pig Peritoneal Macrophages.- Cytological Characteristics of Bone Marrow Reticular Cells, Tissue Macrophages and Monocytic Cell Line.- Leukocyte Enzyme Assays by Flow Cytophotometry.- Section 2 Immunopharmacology of the Reticuloendothelial System.- Alterations of Rat Liver Lysosomes After Treatment With Particulate ? 1–3 Glucan From Saccharomyces cerevisiae.- Suppressor Cell Induction and Reticuloendothelial Cell Activation Produced in the Mouse By ? 1–3 Glucan.- Therapeutic Effect of Intravenously Administered Yeast Glucan, in Mice Locally Infected by Mycobacterium leprae.- Comparative Biological and Antitoxoplasmic Effects of Particulate and Water-Soluble Polysaccharides In Vitro.- Glucan Induced Inhibition of Tumor Growth and Enhancement of Survival in a Variety of Transplantable and Spontaneous Murine Tumor Models.- Glucan Induced Modification of Experimental Staphylococcus aureus Infection in Normal, Leukemic and Immunosuppressed Mice.- Particulate ? 1–3 Glucan and Causal Prophylaxis of Mouse Malaria (Plasmodium berghei).- Restoration of Depressed Antibody Responses of Leukemic Splenocytes Treated with LPS-Induced Factors.- Functional Similarity and Diversity in Peritoneal Macrophage Populations Induced In Vivo by Various Stimuli.- Activation of Pleural Macrophages by Intrapleural Application of Corynebacterium parvum.- Modulation of T Cells and Macrophages by Cholera Toxin Treatment In Vivo and In Vitro.- In Vivo Activation of Murine Peritoneal Macrophages by Nocardia Water Soluble Mitogen (NWSM).- Suppression of Immunological Responsiveness in Aged Mice and Its Relationship with Coenzyme Q Deficiency.- Quercetin, A Regulator of Polymorphonuclear Leukocyte (PMNL) Functions.- The Effect of Cyclophosphamide on A Secondary Ocular Immune Response in Rabbits.- Section 3 Regulatory Functions of the Reticuloendothelial System.- RES Function and Glucose Homeostasis.- Role of RES and Leukocytic Endogenous Mediator in Iron, Zinc and Copper Metabolism.- Function of Macrophage Prostaglandins in the Process of Phagocytosis.- The Mononuclear Phagocyte System and Hemopoiesis.- Macrophages as Regulators of Granulopoiesis.- Regulation of Antigen Binding to T Cells: The Role of Products of Adherent Cells, and the H-2 Restriction of the Antigen Bound.- Alveolar Macrophage — Induced Suppression of the Immune Response.- Suppression of Antibody Forming Cells by Rat Spleen Macrophages.- Section 4 Environmental Factors Influencing the Reticuloendothelial System and Immune Responses.- Environmental Chemical-Induced Modification of Cell-Mediated Immune Responses.- The Immunodepressive Effect of Phenol Derivatives.- Alveolar Macrophage — Splenic Lymphocyte Interactions Following Chronic Asbestos Inhalation in the Rat.- Tobacco Smoke and the Pulmonary Alveolar Macrophage.- Effects of Pesticides on the Reticuloendothelial System.- Substances from Marine Organisms Influencing Tumor Growth and Immune Responses.- Effects of UV Radiation on the Immune System: Consequences for UV Carcinogenesis.- In Vitro and In Vivo Parameters of Humoral and Cellular Immunity in an Animal Model for Protein-Calorie Malnutrition.- Participants.