MSX 1 Gene in Indian Non -Syndromic cleft Population : A Mutation Search

ISBN-13: 9783659237287 / Angielski / Miękka / 2012 / 76 str.

Deepak Chandrasekharan

Opis

Non syndromic clefting has always been thought of being a multifactorial inheritance with the role of a major Gene . Recently the MSX1 gene has been implicated in the cause of non syndromic clefting . The aim of this study was to understand the role of the MSX 1 gene in non-syndromic clefting in South Indian Population .The Study proved the lack of any mutation in MSX 1 gene unlike its association in some caucasian population . This study also establishes the variability of the etiological factors to Non syndromic clefting in the world.

O autorze

Prof.Deepak Chandrasekharan is an Orthodontist and a Faculty at the Department of Orthodontics , Sree Balaji Dental College , Chennai, India . Prof Deepak leads a dedicated cleft palate research team in Bharath University . Genetic Research in Non syndromic cleft plate patients is his team`s primary research Focus .