Living Kidney Donation: Best Practices in Evaluation, Care and Follow-Up

ISBN-13: 9783030536206 / Angielski / Miękka / 2022

Lentine, Krista L.

Opis

This book provides a complete guide to the evaluation, care, and follow-up of living kidney donors. Living donor kidney transplantation is established as the best treatment option for kidney failure. However, despite the tremendous benefits of living donation to recipients and society, the outcomes and optimal care of donors themselves have received relatively less attention. Fortunately, things are changing – including recent landmark developments in living donor risk assessment, policy and guidance.  This volume offers authoritative, evidence-based guidance on the full range of clinical scenarios encountered in the evaluation and care of living kidney donors. The approach to key elements of risk assessment, ethical considerations and informed consent is accompanied by recommendations for patient-centered care before, during, and after donation.  Advocacy initiatives and policies to remove disincentives to donation and advance a defensible system of practice are also discussed. General and transplant nephrologists, as well as related allied health professionals, can look to this book as a comprehensive resource addressing contemporary clinical topics in the practice of living kidney donation.

Spis treści

Introduction

•Organ shortage

•Benefits to recipients of LKDT

•Ethical foundation of donor autonomy within boundaries of ‘acceptable risk’

•Brief mention of Peter Reese work on ‘harms’ that may results from declining a donor candidate

•Landscape of living donation - Epidemiology, trends 

Informed Consent and Framework for Care

•Core principles and processes of informed consent

•Overview of the Living Donor Care Team - Roles & Responsibilities

Medical Evaluation

•GFR, Albuminuria, Hematuria

•Renal anatomy, Nephrolithiasis

•Blood pressure

•Metabolic

•Cancer

•Infections

•Genetics - ADPKD, ApoL1, and other less common 

•Peri-operative screening

Compatibility, Paired Donation, and Incompatible Living Donor Transplants

Psychosocial Evaluation

Risk Assessment 

•New risk calculators for donor ESRD (Grams ‘predonation’, Massie ‘postdonation’)

•New tools for recipient outcomes based on LD characteristics

•Pregnancy-related risks and counseling

Surgical Approaches 

•Comparative data on outcomes, recovery, pain, cosmesis as per the surgical trials.

Follow-up Care

Policy & Ethics

•Core Ethical Tenets & Unacceptable practices.  

•‘Incentives’/paying donors (can be brief – Declaration of Istanbul, note as illegal and most countries, etc)

•Donor Candidate identification (including emerging approaches like Social Media)

•Non-directed donors

•International donors

•Disparities in access to LKDT and strategies to less

•Mitigating barriers/disincentives to living donation – including Financial, Educational/SES/health literacy-related, etc)

O autorze

Krista L. Lentine, MD, PhD

Professor of Medicine

Mid-America Transplant/Jane A. Beckman Endowed Chair in Transplantation

Division of Nephrology / Center for Abdominal Transplantation

Saint Louis University School of Medicine

St. Louis, MO, USA

Beatrice P. Concepcion, MD

Assistant Professor of Medicine

Department of Medicine

Division of Nephrology and Hypertension

Vanderbilt University Medical Center

Nashville, TN, USA

Edgar V. Lerma, MD 

Clinical Professor of Medicine

Department of Medicine

Section of Nephrology

Department of Medicine

University of Illinois at Chicago College of Medicine/ 

Associates in Nephrology, S.C.

Chicago, IL, USA