Lignans: Chemical, Biological and Clinical Properties

ISBN-13: 9780521304214 / Angielski / Twarda / 1990 / 424 str.

D. C. Ayres; J. D. Loike; David C. Ayres

Opis

The volume surveys the chemical, biological, and clinical properties of lignans, providing information on their isolation, purification, identification and chemical synthesis. The volume also explores fully the potential use of these compounds as antitumor agents.

Recenzje

"This is a comprehensive review of the chemistry and pharmocology of the 440 naturally occurring lignans, with some material on the semisynthetic derivatives etoposide and teniposide which find clinical use in cancer treatment. Given the importance and ubiquity of lignans as bioactive natural products, this is a reference work which a practicing chemist cannot afford to be without." International Journal of Pharmacology International Journal of Pharmacology

Spis treści

Preface; Glossary; 1. Introduction; 2. A registry of the natural lignans; 3. Biological and clinical properties of lignans; 4. Etoposide and teniposide; 5. Isolation, purification and initial characterisation; 6. Determination of structure; 7. Biosynthesis; 8. Synthesis; References.