Acknowledgments Foreword by Kathrin Herrmann Preface Meet the Experts Dr. Kathrin Herrmann 7 Dr. Jarrod Bailey 8 Dr. Lindsay Marshall 10 Dr. David DeGrazia 12 Dr. Stacy Lopresti-Goodman 13 Justin Goodman 14 Kathleen (Katie) M. Conlee 15 Part 1: Dogs in Science 1. Early History of Using Dogs in Research Vivisection 18 Anti-vivisectionist 18 Villains or Heroes? 19 A Dog's Purpose: Early Thoughts 20 Why Use Dogs? 21 Europe: The Scientists and Their Dog Experiments 21
Other Discoveries Using Dogs 27 2. The Debate Begins: Researchers Meet Public Outcry Queen Victoria: (1819–1901) 29 Frances Power Cobbe (1822–1904) 31 The Absinthe Scandal and the Regulation of Vivisection 31 Vivisection in the United States 32 "Zoophil-psychosis": Anti-vivisectionists Said to Be Afflicted by Mental Illness 33 Riots, Dog Thieves and Increased Public Scrutiny of Vivisection 34 3. Dogs in Research—Stories and Statistics Human Drug Tragedies Call for More Dogs in Research 40 Heatstroke Experiments 41 Laika (Barker): The First Living Creature to Orbit the Earth 42 Radioactive Beagle Dog Studies 44 Smoking Beagles 45 Narcoleptic Dobermans 46 Dogs in Research Today: Global Statistics 47 4. Dogs and Drug Development How Much Does It Cost to Approve a Drug? 51 Lost in Translation: Dog Models Have Limited Accuracy in Predicting Human Toxicity 53 Drug Disasters 55 Hearing from the Experts: Views on the Relevance of Dog Research 58 5. The Welfare of Dogs in Research The Beagle—The Breed of Choice for Research 61 Undercover Videos Reveal Experiments and Deaths 62 Discoveries in Dog Cognition: A Case for Making Welfare a Priority 64 Laboratory Animal Oversight in the United States 67 Refining Experiments to Reduce Suffering: Are We Doing Enough for Dogs? 70 6. The Ethics of Dog Research—A Human Perspective The Lab: Voices from the Inside 74 Public Opinion: Voices from the Outside 78 A Difficult Question: How Do We Balance Human Benefit Versus Harm to the Dog? 80 What About Us: What Is Our Part in Animal Research? 82 7. Future Technologies Lung-on-a-Chip 84 The Living Heart Project 86 Human-Derived Organoids 88 Who Is Making Non-Animal Technology a Priority? 90 8. Interviews with Global Experts Ending Dog Research … How and When? 93 9. Re-homing Laboratory Dogs Re-homing Policies: Federal and State Efforts 101 Do Former Laboratory Dogs Make Suitable Family Pets? 103 International Studies Confirm the Value of Re-homing Dogs 104 Part 2: To the Rescue 10. Beagle Freedom Project An Interview with Shannon Keith 109 11. Kindness Ranch Animal Sanctuary Kindness Ranch Beginnings 116 An Interview with John Ramer 117 Part 3: Saved—Stories of Rescue, Rehabilitation, and Second Chances 12. Ambassadors for Freedom Teddy 126 George 129 New Beginnings 131 Changing Hearts, Laws and Paws 131 Looking Ahead with Hope 132 Bogart 133 Following My Path 134 The San Diego 10 135 Bogart the Ambassador 135 Laila 136 We're All In… 137 New Beginnings with Laila 139 13. Special Dogs … Special Love Mini and Maria 141 Mini 142 Maria 143 Blind and Brave 144 Lessons to Live By 144 Leo 145 Chosen One 146 A New Normal 147 Seizures 148 Love Beyond Measure 149 Walker 150 14. Two, Three, Four … Just One Beagle More Chief 154 Bronco 156 Roscoe 158 Wyatt 159 Boomer and Koln 160 Boomer 160 Koln 161 A Lucky Surprise 162 Patience, Love and Training 163 Elliot and Bodhi 164 Elliot 165 Bodhi 167 An Odd Paper Obsession 168 Rescue Dogs Award Show 168 15. Beagles Take a Hike … Adventures in the Outdoors Winnie 170 Scarlet 172 Dug 175 16. Wild West Beagles Texas 180 "Texas McGee Killer Talsma" 180 Marty 183 Frozen in Fear 185 Baby Steps 185 A Visit to Prison 187 17. Part of the Family Chandler 188 Roofus 190 Advice for Families 192 A Child's Perspective 193 Maycie 193 18. Sharing the Gift of Healing Connor 197 Early Memories 198 Bouncing Off the Walls 199 The Empath 200 Pearl Grace 201 Definition of Grace 201 Finding Grace 203 Adventures with Grace 203 19. International Rescues—United Kingdom Going Undercover: Three Beagles Rescued 205 Missy 206 Oliver 208 20. International Rescues—Italy Thousands of Beagles Find Freedom 210 Artù 210 Giulia and Giò 213 Chapter Notes Bibliography Index