'Professor Christopher Huang has updated and significantly broadened the scope and the translational endpoints of the classical textbook of Integrative and Cell Physiology Keynes & Aidley's Nerve and Muscle. The result is a comprehensive, well planned, logically presented and extensively referenced monograph. Based on the text and supporting figures, it builds on the strengths of the parent textbook while also providing new in-depth coverage of recent advances in neurophysiology as well as skeletal and cardiac muscle electrophysiology and contractility. The internationally recognized research accomplishments of Professor Huang on key cell physiology mechanisms of the heart and skeletal muscle form the basis of very informative material concerning cardiac rhythm disturbances and some aspects of exercise physiology and aging. This textbook will serve as a valuable resource for undergraduates, graduate students, as well as both basic science and clinical faculty members in Life Sciences.' Wayne Giles, University of Calgary, Canada

Preface; Acknowledgements; List of abbreviations; 1. Structural organization of the nervous system; 2. Resting and action potentials; 3. Background ionic homeostasis of excitable cells; 4. Membrane permeability changes during excitation; 5. Voltage-gated ion channels; 6. Cable theory and saltatory conduction; 7. Neuromuscular transmission; 8. Synaptic transmission in the nervous system; 9. The mechanism of contraction in skeletal muscle; 10. The activation of skeletal muscle; 11. Excitation-contraction coupling in skeletal muscle; 12. Contractile function in skeletal muscle; 13. Cardiac muscle; 14. Ion channel function and cardiac arrhythmogenesis; 15. Smooth muscle; Further reading; References; Index.

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