Key Heterocycle Cores for Designing Multitargeting Molecules

ISBN-13: 9780081020838 / Angielski / Miękka / 2018 / 436 str.

Om Silakari

Spis treści

1. Multitargeting heterocycles - An improved and rational chemical probes for multifactorial diseases 2. Benzimidazole: Journey from a single targeting to a multitargeting nucleus 3. Acridines: A relatively lesser explored heterocycle for multifactorial diseases 4. Flavone: An important scaffold for medicinal chemistry 5. Thiazolidine-2,4-dione: a potential weapon for targeting multiple pathological conditions 6. Oxindole: A nucleus enriched with multi-targeting potential against complex disorders 7. Thiazine: A Versatile Heterocyclic Scaffold for Multifactorial Diseases 8. Indole: As multi-target directed ligands in medicinal chemistry 9. Triazoles: Multidimensional 5-membered nucleus for designing multitargeting agents 10. Benzoxazolinone: A scaffold with diverse pharmacological significance

O autorze

Dr. Om Silakari is an assistant professor in the Department of Pharmaceutical Sciences and Drug Research, Punjabi University, Patiala, India. He received his Ph.D. degree from Dr. Hari Singh Gour University, India and has been teaching and researching in this area for over 10 years. His research areas include computer-assisted drug designing (CADD) of new anti-inflammatory, antidiabetic and anticancer targets, and the synthesis of new lead molecules. In addition to supervising multiple M. Pharm. and PhD students, he has authored two books and published over 60 papers in international journals. Dr Silakari is an active reviewer for many international journals, has been awarded funding for several research projects, and regularly delivers talks at both national and international conferences.