1. Cutting edge research on stem cell applications in joint and bone repair and regeneration 2. Stem Cell-Based Organoid culture system as innovative model of osteoarthritis and other joint/bone diseases 3. Contributions of stem cell engineering to new therapies of joint/bone diseases 4. Roles of innovative genome editing technologies (e.g. CRISPR/Cas9 systems) in stem cell engineering, rheumatic diseases and other joint/bone diseases 5. Preclinical and clinical applications of iPSC technology in modeling osteoarthritis pathologies and testing drugs 6. The gold standard iPSCs in cartilage, joint and bone repair and regeneration 7. Mesenchymal stem cell related therapies for cartilage, joint and bone diseases 8. Advances in animal models for joint and bone diseases 9. Novel Biomaterials for stem cell engineering and bone regeneration 10. General Discussion, Conclusion Remark and Future Direction