Ischemic and Traumatic Brain and Spinal Cord Injuries

ISBN-13: 9780128135969 / Angielski / Miękka / 2018 / 484 str.

Akhlaq A. Farooqui

Spis treści

1. Classification and molecular aspects of neurotraumatic diseases2. Molecular Aspects of Ischemic Injury3. Potential neuroprotective strategies for ischemic injury4. Molecular Aspects of Spinal Cord Injury5. Potential neuroprotective strategies for spinal cord injury6. Molecular Aspects of traumatic brain injury7. Potential neuroprotective strategies for traumatic brain injury8. Molecular Aspects of chronic traumatic encephalopathy9. Potential neuroprotective strategies for chronic traumatic encephalopathy10. Summery and perspective for future research on ischemic, traumatic brain and spinal cord injuries

O autorze

Akhlaq A. Farooqui is a leader in the field of signal transduction processes, lipid mediators, phospholipases, glutamate neurotoxicity, and neurological disorders. He is a research scientist in the Department of Molecular and Cellular Biochemistry at The Ohio State University. He has published cutting edge research on the role of phospholipases A2 in signal transduction processes, generation and identification of lipid mediators during neurodegeneration by lipidomics. He has studied the involvement of glycerophospholipid, sphingolipid-, and cholesterol-derived lipid mediators in kainic acid neurotoxicity, an experimental model of neurodegenerative diseases. Akhlaq A. Farooqui has discovered the stimulation of plasmalogen- selective phospholipase A2 in brains of patients with Alzheimer disease (AD). Stimulation of this enzyme may not only be responsible for the deficiency of plasmalogens in neural membranes of AD patients, but also be related to the loss of synapse in the AD.