The complex transdiagnostic manifestations of pediatric irritability are superbly addressed in this landmark compilation of perspectives by the leaders in the field. This incomparable resource on what is currently known delineates the research agendas in epidemiology, phenomenology, assessment, neuroimaging, genetics, and therapeutics over the next decade. Essential reading for all clinicians and investigators focused on the mental health of children and adolescents.
Amy K. Roy is an Associate Professor of Psychology at Fordham University where she also serves as the Director of the Integrative Neuroscience Program. She has been the recipient of numerous awards including two Young Investigator Awards from the Brain and Behavior Research Foundation (formerly NARSAD), an Anxiety Disorders Association of America Career Development Travel Award, and a New Clinical Drug Evaluation Unit New Investigator's Award. She
has authored/co-authored over 40 peer-reviewed papers and has edited a book on Pediatric Anxiety Disorders.
Melissa A. Brotman is the Director of Neuroscience and Novel Therapeutics, Section on Mood Dysregulation and Neuroscience, Emotion and Development Branch at the National Institute of Mental Health. Currently, her developmental, translational research integrates basic and clinical approaches to the study of mood disorders in children and adolescents. Specifically, she uses affective neuroscience techniques (e.g., fMRI, behavioral
paradigms) to understand the brain-based mechanisms underlying severe irritability in youth, and then uses that pathophysiological knowledge to guide the development of novel targeted interventions. She is on the Editorial Board of the Journal of Affective Disorders. Finally, mentoring is an essential aspect of her career; she was recognized in September 2016 when she received the NIMH Outstanding Mentor Award.
Ellen Leibenluft is a Senior Investigator at the National Institute of Mental Health Intramural Research Program. Her contributions include identifying chronic irritability as an important clinical problem distinct from pediatric bipolar disorder, and using cognitive neuroscience to elucidate the nosology and pathophysiology of pediatric mental disorders, thus enabling the development of novel interventions. She has authored over 250 publications and served as an Editor and
Editorial Board member for multiple journals in her field. She has received many awards, including
the NIMH Director's Merit Award and election to the National Academy of Medicine.