Ion Channels in Health and Disease

ISBN-13: 9780128020029 / Angielski / Miękka / 2016 / 392 str.

Geoffrey S. Pitt

Opis

Ion Channels in Health and Disease provides key insight to allow researchers to generate discoveries across disease states. A single resource that integrates disparate areas of biology and disease ion channel biology, this publication includes cross-referencing for disease, channels, and tissues. Offers a broad view of research of interest to early and experienced researchers across biological and biomedical research.

• Provides an overview of fundamental concepts in ion channels research to link defects in human disease
• Written in an accessible manner, without jargon
• Provides a helpful, easy cross-reference for diseases, channels, and tissues

Spis treści

1. Calcium channel auxiliary subunits in pain management
2. Sodium channels and pain
3. Voltage-gated ion channels in cancer
4. Novel channels regulating somatosensation
5. Ion channels in epilepsy
6. Skeletal myopathies caused by channelopathies
7. Endocrine disorders caused by channelopathies
8. Emerging roles of CaCC channels in health and disease
9. New roles for ion channels in neuropsychiatric disorders
10. Pharmacology and pathophysiology of calcium channels
11. Inherited cardiac arrhythmias
12. Ion channels and diabetes
13. Migraines and calcium channels
14. Immunity and ion channels

O autorze

Geoffrey S. Pitt is the Ida and Theo Rossi Distinguished Professor of Medicine at Weill Cornell Medicine and the Director of the Cardiovascular Research Institute. His current research investigates the structure, function and regulation ion channels and the disease that occur ("channelopathies”) from abnormal ion channel function. His laboratory's use electrophysiology, biochemistry, structural biology, and animal models to discern how channelopathies cause diseases such as cardiac arrhythmias, epilepsy, autism, and ataxias.