Ion Channel Pharmacology

ISBN-13: 9780198523604 / Angielski / Twarda / 1998 / 488 str.

Cena Soria; Valentin Cena; Bernat Soria

Opis

The pharmacology of ion channels is becoming increasingly important. M olecular biology techniques have led to the better understanding of io n channel structure which has opened the way for the development of ne w drugs targeted at specific types of ion channels. This volume provid es a fully comprehensive, single-volume overview of the effects of dif ferent drugs and toxins on ionic channels. The first part of the book deals with the development of ion channels. Subsequent chapters offer detailed descriptions of the electrophysiological properties and pharm acology of eight different types of ion channels, including material o n intracellular, cyclic nucleotide-gated, and receptor operated channe ls. For each channel type, the effects of different drugs in various c ell types are discussed, along with the potential roles of channels in therapeutics. Clearly written, Ion Channel Pharmacology will be an es sential reference tool for all researchers in this topical and fast-gr owing subject area.