Introduction to Spatial Mapping of Biomolecules by Imaging Mass Spectrometry

ISBN-13: 9780128189986 / Angielski / Miękka / 2021 / 272 str.

Bindesh Shrestha

Spis treści

1. Fundamentals of Imaging Mass Spectrometry2. Ionization Source for Imaging Mass Spectrometry3. Sample Preparation and MALDI Matrix Applications4. Tissue Sectioning for Imaging Mass Spectrometry5. Matrix for Matrix-assisted Laser Desorption/Ionization (MALDI)6. Molecule Identification Approaches in Imaging Mass Spectrometry7. Quantitation Workflow in Imaging Mass Spectrometry8. Spatial Resolution of Imaging Mass Spectrometry9. Visualization of Imaging Mass Spectrometry10. Analysis of imaging mass spectrometry data11. Multimodal imaging mass spectrometry12. Validation and Standardization of Imaging Mass Spectrometry13. Towards Clinical Imaging Mass Spectrometry14. Case study: Imaging N-Glycan on tissue15. Case study: Reactive matrix and neurotransmitters and brain metabolites16. Case study: Endogenous metabolites in mammalian tissues17. Case study: Imaging of small drug molecules18. Case study: Imaging Gangliosides

O autorze

Dr. Bindesh Shrestha is a senior scientist at the Waters Corporation focusing on imaging mass spectrometry. He has co-authored more than two dozen peer-reviewed articles in the field of mass spectrometry spanning over the last decade. His publications have been featured multiple times on the covers of leading journals, including Angewandte Chemie, Analytical Chemistry, Analyst, and more.